6558-66-3 Usage
General Description
7-METHYLIMIDAZO[1,2-A]PYRIMIDINE, also known as 7-MIP, is a chemical compound with the molecular formula C6H6N4. It is a derivative of imidazo[1,2-a]pyrimidine and is used as a building block in the synthesis of pharmaceutical compounds and other organic molecules. 7-METHYLIMIDAZO[1,2-A]PYRIMIDINE has potential applications in the development of new drugs, particularly in the field of anti-cancer and anti-inflammatory medications. It may also be used as a research tool in chemical and biological studies. Its molecular structure and properties make it a versatile and valuable chemical in various scientific and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6558-66-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6558-66:
(6*6)+(5*5)+(4*5)+(3*8)+(2*6)+(1*6)=123
123 % 10 = 3
So 6558-66-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c1-6-2-4-10-5-3-8-7(10)9-6/h2-5H,1H3
6558-66-3Relevant articles and documents
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABAAα2/α3 binding site agonists for the treatment of anxiety disorders
Goodacre, Simon C.,Street, Leslie J.,Hallett, David J.,Crawforth, James M.,Kelly, Sarah,Owens, Andrew P.,Blackaby, Wesley P.,Lewis, Richard T.,Stanley, Joanna,Smith, Alison J.,Ferris, Pushpinder,Sohal, Bindi,Cook, Susan M.,Pike, Andrew,Brown, Nicola,Wafford, Keith A.,Marshall, George,Castro, José L.,Atack, John R.
, p. 35 - 38 (2007/10/03)
A series of high-affinity GABAA agonists with good oral bioavailability in rat and dog and functional selectivity for the GABA Aα2 and -α3 subtypes is reported. The 7-trifluoromethylimidazopyrimidine 14g and the 7-propan-2-olimidazopyrimidine 14k are anxiolytic in both conditioned and unconditioned animal models of anxiety with minimal sedation observed at full BZ binding site occupancy.
