6558-66-3 Usage
Uses
Used in Pharmaceutical Industry:
7-METHYLIMIDAZO[1,2-A]PYRIMIDINE is used as a building block for the synthesis of pharmaceutical compounds, particularly in the development of new drugs for anti-cancer and anti-inflammatory treatments. Its molecular structure allows for the creation of various derivatives with potential therapeutic properties.
Used in Chemical Research:
7-METHYLIMIDAZO[1,2-A]PYRIMIDINE serves as a research tool in chemical studies, enabling scientists to explore its properties and potential applications in the synthesis of new organic molecules.
Used in Biological Studies:
As a versatile chemical, 7-METHYLIMIDAZO[1,2-A]PYRIMIDINE is also used in biological studies to investigate its interactions with biological systems and its potential as a therapeutic agent.
Check Digit Verification of cas no
The CAS Registry Mumber 6558-66-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6558-66:
(6*6)+(5*5)+(4*5)+(3*8)+(2*6)+(1*6)=123
123 % 10 = 3
So 6558-66-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c1-6-2-4-10-5-3-8-7(10)9-6/h2-5H,1H3
6558-66-3Relevant academic research and scientific papers
Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABAAα2/α3 binding site agonists for the treatment of anxiety disorders
Goodacre, Simon C.,Street, Leslie J.,Hallett, David J.,Crawforth, James M.,Kelly, Sarah,Owens, Andrew P.,Blackaby, Wesley P.,Lewis, Richard T.,Stanley, Joanna,Smith, Alison J.,Ferris, Pushpinder,Sohal, Bindi,Cook, Susan M.,Pike, Andrew,Brown, Nicola,Wafford, Keith A.,Marshall, George,Castro, José L.,Atack, John R.
, p. 35 - 38 (2007/10/03)
A series of high-affinity GABAA agonists with good oral bioavailability in rat and dog and functional selectivity for the GABA Aα2 and -α3 subtypes is reported. The 7-trifluoromethylimidazopyrimidine 14g and the 7-propan-2-olimidazopyrimidine 14k are anxiolytic in both conditioned and unconditioned animal models of anxiety with minimal sedation observed at full BZ binding site occupancy.
