65597-47-9

Usage

Uses

Used in Pharmaceutical Industry:
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-3,4-dihydro-2H-chromen-7-yl beta-D-xylopyranoside is used as a pharmaceutical agent for its potential anti-inflammatory and anti-cancer effects. Its antioxidant properties and presence in various plant sources make it a promising candidate for the development of new drugs and therapies.
Used in Nutraceutical Industry:
In the nutraceutical industry, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-3,4-dihydro-2H-chromen-7-yl beta-D-xylopyranoside is used as a dietary supplement to promote overall health and well-being. Its potential health benefits, such as anti-inflammatory and anti-cancer effects, make it a valuable addition to dietary supplements and functional foods.
Used in Cosmetic Industry:
(2R,3S)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-3,4-dihydro-2H-chromen-7-yl beta-D-xylopyranoside is used in the cosmetic industry for its antioxidant properties. It can be incorporated into skincare products to protect the skin from oxidative stress and promote a healthy complexion.
Used in Food and Beverage Industry:
In the food and beverage industry, (2R,3S)-2-(3,4-dihydroxyphenyl)-3,5-dihydroxy-3,4-dihydro-2H-chromen-7-yl beta-D-xylopyranoside is used as a natural antioxidant to extend the shelf life of products and maintain their quality. Its presence in various plant sources makes it a suitable ingredient for the development of functional foods and beverages with health-promoting properties.

Upstream product

• 6858-46-4 uridine 5'-diphosphoglucose disodium salt 
• 154-23-4 catechin 
• 133-89-1 UDP-glucose 
• 105330-39-0 (2S,3R,4S,5S,6R)-2-[(2R,3R)-4-Benzylsulfanyl-2-(3,4-dihydroxy-phenyl)-3,5-dihydroxy-chroman-7-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 

Downstream Products

• 154-23-4 catechin 
• 29127-26-2 5,3',4'-tri-O-methyl-(+)-catechin 
• 65597-49-1 (2S,3R,4S,5S,6R)-2-[(2R,3S)-2-(3,4-Dimethoxy-phenyl)-3-hydroxy-5-methoxy-chroman-7-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 

Relevant academic research and scientific papers

New flavanol O-glycosides in grape and wine

The presence of monomeric and dimeric flavan-3-ol monohexosides was investigated in grapes and wines. Polyphenol extracts were prepared from grape seeds and skins (Syrah, Merlot, and Cabernet-Sauvignon) sampled at three different developmental stages. Different wines (Tannat, Alicante, Syrah, Merlot, and Grenache) were also studied. The different samples obtained were analyzed by UPLC-ESI-IT-MS. Specific molecular ions corresponding to flavan-3-ol hexosides were detected by using targeted molecular ions with specific m/z values: 451 for (epi)catechin hexosides, and 739 for procyanidin dimer hexosides. 4′-O-β-glucosyl-(+)-catechin and 7-O-β-glucosyl-(+)-catechin were obtained by using a glucosyl transferase from apple, UGT71A15, and their structures determined by NMR. These glucosylated monomers and the dimers were identified in all analyzed grape seed and several skin extracts at the different stages and in wines made from different varieties.

Catechin Glucosides: Occurrence, synthesis, and stability

Catechins are flavonoids with suggested health benefits, but are unstable during storage, processing and, after ingestion, during gut transit. We hypothesized that catechin glucosidos, which occur in various plants, could be more stable than unsubstituted catechin, and additionally be deglucosylated in the gut and so act to deliver catechin in a form able to be absorbed. (+)-Catechin O-glucosides from various sources have been used in the course of this investigation. (+)-Catechin 3'-O-β-D-glucopyranoside (C3'G), (+)-catechin 5-O-β-D-glucopyranoside (C5G), and (+)-catechin 3-O-β-D-glucopyranoside (C3G) were chemically synthesized. (+)-Catechin 4'-O-β-D-glucopyranoside (C4'G) and (+)-catechin 7-O-β-D-glucopyranoside (C7G) were prepared enzymically using preparations from lentil and barley. In general, but with some exceptions, the (+)-catechin glucosidos were more stable between pH 4 and 8 than (+)-catechin, with C3'G exhibiting greatest stability. The intestinal metabolism of (+)-catechin and all (+)-catechin glucosides in the gut was determined by perfusion of rat intestine in vivo. C3'G and C5G were extensively deglycosylated in the gut, and C3'G showed greatest apparent "absorption" as calculated by the difference between effluent and influent. The results show the potential of catechin glucosides, especially C3'G, as more stable prescursors of catechin.

GLUCOSYLATION OF PHENOLICS BY HAIRY ROOT CULTURES OF LOBELIA SESSILIFOLIA

Two new glucosides, (-)-epiafzelechin 7-O-β-D-glucopyranoside and photocatechuic acid 3-O-β-D-glucopyranoside were isolated from hairy roots of Lobelia sessilifolia after cultivation with (-)-epicatechin or protocatechuic acid, respectively. - Keywords: L