65600-05-7Relevant articles and documents
Ir-Catalyzed Selective B(3)-H Amination of o-Carboranes with NH3
Au, Yik Ki,Zhang, Jie,Quan, Yangjian,Xie, Zuowei
, p. 4148 - 4153 (2021)
Ammonia gas, NH3, is a cheap and widely used industrial feedstock, which has received tremendous research interests in its functionalization. This work reports a breakthrough in catalytic selective cage B(3)-H amination of o-carboranes with NH3 via Ir-catalyzed B-H/N-H dehydrocoupling, offering convenient and efficient access to a series of 3-NH2-o-carborane derivatives in moderate to high isolated yields with a broad substrate scope. The employment of readily available NH3 gas as the aminating reagent with H2 as the sole byproduct endows the protocol economy, practicability, and environmental friendliness. A plausible reaction mechanism is proposed on the basis of control experiments.
