65601-22-1Relevant academic research and scientific papers
Reduction of Lactams and Thiolactams by Sodium Borohydride: Application in the Synthesis of Some Alkaloids
Mandal, S. B.,Giri, V. S.,Sabeena, M. S.,Pakrashi, S. C.
, p. 4236 - 4241 (2007/10/02)
Lactams 1a-8a and thiolactams 1b-8b,9a,10b-12b and 13 could be reduced to their corresponding amines in 70-98percent yield by using borohydide-tert-butyl alcohol-methanol mixtures under reflux.Even the vinylogous amide 19 underwent reduction to afford dep
