65613-01-6Relevant academic research and scientific papers
Synthesis and antibacterial activity of some 5,5'-(1,4-phenylene)-bis-1,3, 4-oxadiazole and bis-1,2,4-triazole derivatives as precursors of new S-nucleosides
Datoussaid, Yazid,Othman, Adil A.,Kirsch, Gilbert
experimental part, p. 30 - 35 (2012/06/04)
Five compounds, namely 5,5'-benzene-1,4-diylbis(1,3,4-oxadiazole-2-thiol)6 and 5,5'-benzene-1,4-diylbis(1H-1,2,4-triazole-3-thiol) 7a and its derivatives 7b-d were synthesized. Two related S-nucleosides 9 and 10 have been prepared from 6 and 7a. Some of these synthesized compounds were tested in vitro by spotting on Mueller Hinton Agar medium against some Gram-positive bacteria, Staphylococcus aureus and Enterococcus faecalis and three Gram-negative bacteria Escherichia coli, Pseudomonasaeruginosa, Pseudomonas fluorescens and compared with the known antibiotics cephalosporin (cefotaxim) and gentamycin. Compound 6 showed significant inhibitory activity against Gram-positive E. faecalis and Gram-negative E. coli bacteria while the others have shown variable inhibition activity.
Synthesis and mesomorphic behavior of some novel compounds containing 1,3,4-Thiadiazole and 1,2,4-Triazole rings
Tomma, Jumbed H.,Rou'Il, Ivan H.,Al-Dujaili, Amar H.
experimental part, p. 3 - 19 (2010/04/02)
Two new mesogenic homologous series of liquid crystalline compounds containing 1,2,4-triazole and 1,3,4-thiadiazole in the molecule viz. 1,4-bis{3-[2-(4-alkoxybenzelideneamino)-1,3,4-thiadiazole-5-ethylenethio]1,2, 4-triazole-5-yl}phenyl and 5-(4-methoxyp
