65619-01-4

Basic information

• Product Name: 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE
• Synonyms: 4-oxo-1-p-tolylcyclohexanecarbonitrile;4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE
• CAS NO: 65619-01-4
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.279
• Mol File: 65619-01-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE(65619-01-4)
• EPA Substance Registry System: 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE(65619-01-4)

Safety Data

• Hazardous Substances Data: 65619-01-4(Hazardous Substances Data)

Usage

Description

4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE is a chemical compound characterized by the molecular formula C16H17NO. It is a ketone derivative featuring a cyclohexane ring to which a cyano group and a 4-methylphenyl group are attached. 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE is recognized for its role in organic synthesis and pharmaceutical research, where it serves as a versatile building block for the creation of various pharmaceuticals and agrochemicals. Additionally, it holds potential for the development of new materials and as a reagent in chemical reactions. Due to its chemical nature, it is crucial to handle 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE with care, adhering to safety protocols and guidelines to mitigate any hazardous properties it may possess.

Uses

Used in Pharmaceutical Research:
4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE is utilized as a key building block in the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of a wide range of medicinal compounds with potential applications in treating various diseases and conditions.
Used in Agrochemical Development:
In the agrochemical industry, 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE serves as a crucial intermediate in the synthesis of various agrochemicals. Its incorporation aids in the development of pesticides, herbicides, and other agricultural chemicals that are essential for enhancing crop protection and yield.
Used in Material Science:
4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE holds potential in material science for the development of new materials with unique properties. Its structural attributes make it a valuable component in the synthesis of advanced materials for various applications, including high-performance polymers and composites.
Used as a Chemical Reaction Reagent:
In the realm of chemical reactions, 4-CYANO-4-(4-METHYLPHENYL)CYCLOHEXANONE functions as a reagent, facilitating specific transformations and processes. Its presence can enhance the efficiency and selectivity of certain reactions, making it a valuable tool in the synthesis of complex organic molecules.

Upstream product

• 56326-94-4 methyl 5-cyano-5-(4-chlorophenyl)-2-oxocyclohexanecarboxylate 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 65619-00-3 2-carbomethoxy-4-cyano-4-(p-tolyl)cyclohexanone 
• 65618-99-7 4-Cyano-4-(p-tolyl)-pimelinsaeuredimethylester 

Downstream Products

• 65619-02-5 4-cyano-4-(p-tolyl)cyclohexanone, ethylene ketal 
• 77253-86-2 4-dimethylamino-4-(p-tolyl)cyclohexan-1-one, ethylene ketal 
• 65619-03-6 4-isocyanato-4-(p-tolyl)cyclohexanone, ethylene ketal 
• 65653-88-5 4-carboxy-4-(p-tolyl)cyclohexanone, ethylene ketal 
• 65619-04-7 4-methylamino-4-(p-tolyl)cyclohexanone, ethylene ketal 

Relevant articles and documents

DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

The present invention relates to di(hetero)arylcyclohexane derivatives of the formula (I), in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmaceutical active compounds which inhibit ATP-sensitive potassium channels in the heart muscle and are suitable, for example, for the treatment of disorders of the cardiovascular system such as arrhythmias or a decreased contractility of the heart, such as can occur, for example, in coronary heart disease, cardiac insufficiency or cardiomyopathies. In particular, they are suitable for the prevention of sudden cardiac death. The invention furthermore relates to processes and intermediates for the preparation of the compounds of the formula (I), their use and pharmaceutical compositions comprising them.

4-Amino-4-phenylcyclohexanone ketal compositions and process of use

A class of new 4-amino-4-arylcyclohexanones, their ketals, and acid addition salts have been synthesized and found to be useful for relieving pain in animals. Their analgesic activity appears to be of high order, and in addition some exhibit narcotic antagonist activity that is useful in modifying the cardiovascular, respiratory, and behavioral depression caused by other analgesics. Several show mixed analgesic and narcotic antagonist activity. Preferred compounds of the class are 4-(m-hydroxyphenyl)-4-dimethylaminocyclohexanone ethylene ketal, and 4-(m-hydroxyphenyl)-4-(n-butylmethylamino)cyclohexanone ethylene ketal as free bases and as their hydrochloride salts. Processes for synthesis and intermediates are described. Unit dosage forms and therapeutic treatments are disclosed.