65619-29-6

Basic information

• Product Name: 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE
• Synonyms: 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE;1-(3-chlorophenyl)-4-oxocyclohexanecarbonitrile
• CAS NO: 65619-29-6
• Molecular Formula: C₁₃H₁₂ClNO
• Molecular Weight: 233.69348
• Mol File: 65619-29-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE(65619-29-6)
• EPA Substance Registry System: 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE(65619-29-6)

Safety Data

• Hazardous Substances Data: 65619-29-6(Hazardous Substances Data)

Usage

General Description

4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE is a chemical compound with the molecular formula C14H14ClNO. It is a cyclohexanone derivative that contains a cyanide group and a 3-chlorophenyl group. 4-CYANO-4-(3-CHLOROPHENYL)CYCLOHEXANONE is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential antimalarial and anti-inflammatory properties. Additionally, it may have applications in organic synthesis and as a building block for the preparation of various organic compounds. However, it is important to handle and use this chemical with caution, as it can be toxic and harmful if not properly handled.

Upstream product

• 65619-21-8 4-(3-chloro-phenyl)-4-cyanoheptanedioic acid dimethyl ester. 
• 1529-41-5 3-chloro-benzeneacetonitrile 
• 65619-25-2 5-(3-chlorophenyl)-5-cyano-2-oxo-cyclohexanecarboxylic acid methyl ester 

Downstream Products

• 1037235-24-7 [8-(3-chlorophenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyl]carbamic acid tert-butyl ester 
• 1037197-18-4 C₂₃H₃₄Cl₂N₂O₃ 
• 1037236-27-3 C₁₈H₂₅ClN₄O₂ 
• 1037235-85-0 methanesulphonic acid [trans-4-(tert-butoxycarbonylaminomethyl)-4-(3-chlorophenyl)cyclohexyl] ester 
• 1552306-25-8 C₂₉H₃₆ClF₃N₄O₂ 
• 1552306-29-2 C₂₉H₃₄ClF₃N₄O₃ 
• 1037235-28-1 ({cis-1-(3-chlorophenyl)-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]cyclohexyl}methyl)-carbamic acid tert-butyl ester 
• 1037235-38-3 [1-(cis-3-chlorophenyl)-4-(8-oxo-3-trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)cyclohexylmethyl]carbamic acid tert-butyl ester 
• 1037235-26-9 [1-(3-chlorophenyl)-4-oxo-cyclohexylmethyl]-carbamic acid tert-butyl ester 
• 887978-99-6 C-[8-(3-chlorophenyl)-1.4-dioxa-spiro[4.5]dec-8-yl]methylamine 
• 1037360-81-8 C₂₄H₂₈ClF₃N₄ 
• 1037361-22-0 C₂₄H₂₆ClF₃N₄O 
• 1037360-33-0 1-{cis-1-(3-chlorophenyl)-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]cyclohexyl}methanamine 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS

This invention relates to compounds that are agonists of the muscarinic M1 receptor or M1 and M4 receptors and which are useful in the treatment of muscarinic M1 or M1/M4 receptor mediated

DI(HETERO)ARYLCYCLOHEXANE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

The present invention relates to di(hetero)arylcyclohexane derivatives of the formula (I), in which Ar1, Ar2, R1 and R2 have the meanings indicated in the claims. The compounds of the formula (I) are valuable pharmaceutical active compounds which inhibit ATP-sensitive potassium channels in the heart muscle and are suitable, for example, for the treatment of disorders of the cardiovascular system such as arrhythmias or a decreased contractility of the heart, such as can occur, for example, in coronary heart disease, cardiac insufficiency or cardiomyopathies. In particular, they are suitable for the prevention of sudden cardiac death. The invention furthermore relates to processes and intermediates for the preparation of the compounds of the formula (I), their use and pharmaceutical compositions comprising them.