656223-61-9Relevant academic research and scientific papers
Asymmetric Allylic Amination in Water Catalyzed by an Amphiphilic Resin-Supported Chiral Palladium Complex
Uozumi, Yasuhiro,Tanaka, Hirotaka,Shibatomi, Kazutaka
, p. 281 - 283 (2007/10/03)
(Matrix presented) Catalytic asymmetric allylic amination of cycloalkenyl carbonates (methyl cyclohexen-2-yl carbonate, methyl cyclohepten-2-yl carbonate, methyl 5-methoxycarbonylcyclohexen-2-yl carbonate, methyl cyclohexenyl carbonate, tert-butyl 5-methoxycarbonyloxy-1,2,5,6- tetrahydropyridinedicarboxylate) with dibenzylamines ((C6H 5CH2)2NH, (C6H5CH 2)(4-CH3OC6H4CH2)NH, (4-CH3OC6H4CH2)2NH) was achieved in water under heterogeneous conditions by use of a palladium complex of (3R,9aS)-3-[2-(diphenylphosphino)phenyl]-2-phenyltetrahydro-1H-imidazo[1,5-a] indole-1-one anchored on polystyrene-poly(ethylene glycol) copolymer resin to give the corresponding cycloalkenylamines with high enantiomeric selectivity (90-98% ee).
