656227-40-6

Basic information

• Product Name: 2-Thiophenecarboxylic acid, 5-(5-nitro-2-pyridinyl)-
• Synonyms: 5-(5-nitropyridin-2-yl)thiophene-2-carboxylic acid
• CAS NO: 656227-40-6
• Molecular Formula: C₁₀H₆N₂O₄S
• Molecular Weight: 250.23
• Product Categories: Carboxylic Acids;Thiophenes & Benzothiophenes;Carboxylic Acids;Thiophenes & Benzothiophenes
• Mol File: 656227-40-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Thiophenecarboxylic acid, 5-(5-nitro-2-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxylic acid, 5-(5-nitro-2-pyridinyl)-(656227-40-6)
• EPA Substance Registry System: 2-Thiophenecarboxylic acid, 5-(5-nitro-2-pyridinyl)-(656227-40-6)

Safety Data

• Hazardous Substances Data: 656227-40-6(Hazardous Substances Data)

Upstream product

• 4487-59-6 2-bromo-5-nitropyridine 

Downstream Products

• 656224-99-6 5-(5-phenethylamino-pyridin-2-yl)-thiophene-2-carboxylic acid methyl ester 
• 656227-33-7 5-(5-amino-pyridin-2-yl)-thiophene-2-carboxylic acid methyl ester 

Relevant articles and documents

Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors

Further investigation of a series of thienyl-based hydroxamic acids that included ADS100380 and ADS102550 led to the identification of the 5-pyridin-2-yl-thiophene-2-hydroxamic acid 3c, which possessed modest HDAC inhibitory activity. Substitution at the

SUBSTITUTED THIENYL-HYDROXAMIC ACIDS AS HISTONE DEACETYLASE INHIBITORS

A compound of formula (I): which can be used in the treatment of diseases associated with histone deacetylase enzymatic activity.