65623-99-6

Usage

General Description

1H-Isoindole-1,3(2H)-dione, 2-[3-(4-acetylphenoxy)propyl]- is a chemical compound that contains an isoindole ring with a 2-[3-(4-acetylphenoxy)propyl]- side chain attached to it. 1H-Isoindole-1,3(2H)-dione, 2-[3-(4-acetylphenoxy)propyl]- is a member of the isoindole-1,3-dione family, which is characterized by a five-membered ring with two ketone groups at positions 1 and 3. The side chain in 1H-Isoindole-1,3(2H)-dione, 2-[3-(4-acetylphenoxy)propyl]- consists of a 3-(4-acetylphenoxy)propyl group, which is a combination of a 3-carbon propyl chain linked to a phenyl ring with an acetyl group attached to it. 1H-Isoindole-1,3(2H)-dione, 2-[3-(4-acetylphenoxy)propyl]- may have various industrial, pharmaceutical, or research applications due to its specific chemical structure and properties.

Upstream product

• 65623-98-5 1-[4-(3-bromopropoxy)phenyl]ethanone 
• 1074-82-4 potassium phtalimide 
• 5460-29-7 2-(3-bromopropyl)isoindole-1,3-dione 
• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 1443997-40-7 10-[4-(3-Aminopropyloxy)benzoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid tris(1,1-dimethylethyl) ester 
• 1443997-39-4 10-[4-(3-Phthalimidopropyloxy)benzoylmethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid tris(1,1-dimethylethyl)ether 
• 1443997-38-3 3-[4-(2-bromoacetyl)phenoxy]-propylphthalimide 

Relevant academic research and scientific papers

A highly sensitive luminescent lectin sensor based on an α-d-mannose substituted Tb3+ antenna complex

Lectin-carbohydrate interactions are the basis of many biological processes and essentially they constitute the language through which intercellular communications are codified. Thus they represent powerful tools in the examination and interpretation of changes that occur on cell surfaces during both physiological and, more importantly, pathological events. The development of optical techniques that exploit the unique properties of luminescent lanthanoid metal complexes in the investigation of lectin-carbohydrate recognition can foster research in the field of ratiometric biosensing and disease detection. Here we report the synthesis of a Tb3+-DO3A complex (Tb?1) bearing an α-d-mannose residue and the related study of binding affinity with concanavalin A (Con A) labeled with rhodamine-B- isothiocyanate (RITC-Con A). Luminescence spectroscopy and dynamic studies show changes in emission spectra that can be ascribed to a luminescence resonance energy transfer (LRET) from Tb?1 (donor) to RITC-Con A (acceptor). The binding constant value between the two species was found to be one order of magnitude larger than those previously reported for similar types of recognition. To the best of our knowledge this is the first example of the use of a pre-organized luminescent lanthanoid complex in the study of carbohydrate-protein interactions by LRET. The Royal Society of Chemistry 2013.

Substituted phenylacetic acid compounds and process for preparation thereof

Substituted phenylacetic acid compounds represented by the following general formula and preparation thereof: STR1 wherein R1 is hydrogen or protected carboxy, R2 is hydrogen, or protected amino, provided that when R1 is h