656233-41-9Relevant academic research and scientific papers
Synthesis and evaluation of a DHA and 10-hydroxycamptothecin conjugate
Wang, Yuqiang,Li, Lianfa,Jiang, Wei,Larrick, James W.
, p. 5592 - 5599 (2007/10/03)
We have synthesized a conjugate of cis-4,7,10,13,16,19-docosahexenoic acid (DHA) and 10-hydroxycamptothecin (HCPT), DHA-HCPT. The antitumor activity of DHA-HCPT was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models in
Novel anticancer conjugates of camptothecin and unsaturated fatty acids
-
Page/Page column 12; Sheet 1, (2008/06/13)
The present invention provides novel conjugates of camptothecin compounds and long-chain unsaturated fatty acid. The novel conjugates can be used to treat mammalian cell proliferative diseases such as cancer.
