656235-65-3

Basic information

• Product Name: (3R,4aR,6aR,7S,10aS,10bR)-3,7,10a-Trimethyl-4a-(toluene-4-sulfonyloxymethyl)-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester
• Synonyms: (3R,4aR,6aR,7S,10aS,10bR)-3,7,10a-Trimethyl-4a-(toluene-4-sulfonyloxymethyl)-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester
• CAS NO: 656235-65-3
• Molecular Weight: 504.688
• Mol File: 656235-65-3.mol

Chemical Properties

• CAS DataBase Reference: (3R,4aR,6aR,7S,10aS,10bR)-3,7,10a-Trimethyl-4a-(toluene-4-sulfonyloxymethyl)-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4aR,6aR,7S,10aS,10bR)-3,7,10a-Trimethyl-4a-(toluene-4-sulfonyloxymethyl)-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester(656235-65-3)
• EPA Substance Registry System: (3R,4aR,6aR,7S,10aS,10bR)-3,7,10a-Trimethyl-4a-(toluene-4-sulfonyloxymethyl)-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester(656235-65-3)

Safety Data

• Hazardous Substances Data: 656235-65-3(Hazardous Substances Data)

Upstream product

• 656235-62-0 (3R,4aR,6aR,7S,10aS,10bR)-3-Formyl-4a-hydroxymethyl-3,7,10a-trimethyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 656235-64-2 (3R,4aR,6aR,7S,10aS,10bR)-4a-Hydroxymethyl-3,7,10a-trimethyl-3-vinyl-dodecahydro-benzo[f]chromene-7-carboxylic acid methyl ester 

Relevant articles and documents

Highly Diastereoselective Synthesis of Manoyl Oxide Derivatives by TiCl4-Catalyzed Nucleophilic Cleavage of Ambracetal Derivatives

The treatment of acetal 11 with KCN and AlCNEt2 in the presence of TiCl4 produces in high diastereoselectivity 2-cyanooxane 14, which can be easily converted into manoyl oxide derivatives. Using this strategy, 19-hydroxymanoyl oxide 20, diterpene from P. viscosum, was prepared from communic acids 7a-c after an 8-steps sequence in a 17% overall yield.