2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one, also known as rimiterol, is a bicyclic chemical compound with the molecular formula C11H15NO. It features a pyridine ring fused to a cyclopentane ring and a ketone functional group. Rimiterol has been studied for its potential therapeutic applications, particularly as a bronchodilator and anti-inflammatory agent for respiratory disorders and as a treatment for glaucoma due to its ability to reduce intraocular pressure.

65645-83-2

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Basic information
1. Product Name: 2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one
2. Synonyms:
3. CAS NO:65645-83-2
4. Molecular Formula:
5. Molecular Weight: 175.23
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: 398-400 °C (decomp)
2. Boiling Point: 343.1±35.0 °C(Predicted)
3. Flash Point: N/A
4. Appearance: N/A
5. Density: 1.20±0.1 g/cm3(Predicted)
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: 2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one(CAS DataBase Reference)
10. NIST Chemistry Reference: 2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one(65645-83-2)
11. EPA Substance Registry System: 2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one(65645-83-2)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 65645-83-2(Hazardous Substances Data)

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Uses

Used in Pharmaceutical Industry:
2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one is used as a bronchodilator for the treatment of respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). It functions by stimulating beta-adrenergic receptors, leading to the relaxation of smooth muscles in the airways and resulting in bronchodilation, which improves airflow and alleviates respiratory symptoms.
2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one is also used as an anti-inflammatory agent in the treatment of respiratory disorders. Its anti-inflammatory properties help reduce inflammation in the airways, further improving respiratory function and reducing symptoms associated with respiratory conditions.
Used in Ophthalmology:
2,3,4,5,6,7-Hexahydro-1H-dicyclopenta[b,e]pyridin-8-one is used in the treatment of glaucoma, a condition characterized by increased intraocular pressure that can lead to optic nerve damage and vision loss. Rimiterol has been studied for its potential to decrease intraocular pressure, making it a candidate for the development of new glaucoma treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 65645-83-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,4 and 5 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65645-83:
(7*6)+(6*5)+(5*6)+(4*4)+(3*5)+(2*8)+(1*3)=152
152 % 10 = 2
So 65645-83-2 is a valid CAS Registry Number.

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