65653-64-7

Basic information

• Product Name: 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol
• CAS NO: 65653-64-7
• Molecular Formula: C₁₀H₇F₆IO
• Molecular Weight: 384.0569
• Mol File: 65653-64-7.mol

Chemical Properties

• Boiling Point: 307.8°C at 760 mmHg
• Flash Point: 140°C
• Density: 1.844g/cm³
• Vapor Pressure: 0.000307mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol(65653-64-7)
• EPA Substance Registry System: 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol(65653-64-7)

Safety Data

• Hazardous Substances Data: 65653-64-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol is used as an intermediate for the production of various pharmaceuticals. Its unique structure and stability allow for the creation of new drugs with enhanced properties and efficacy.
Used in Agrochemical Industry:
In the agrochemical sector, 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol is utilized as a key component in the synthesis of agrochemicals. Its inertness and stability make it suitable for developing compounds that can improve agricultural productivity and pest control.
Used in Specialty Chemicals:
1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol is employed as a building block for the development of specialty chemicals. Its properties enable the creation of chemicals with specific applications, such as in the manufacturing of high-performance materials.
Used as a Solvent in Chemical Reactions:
Due to its high boiling point and low vapor pressure, 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol is used as a solvent in various chemical reactions. Its stability and inertness make it an ideal choice for processes that require a non-reactive medium.
Used in the Development of New Materials:
The unique structure of 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol allows for its use in the development of new materials with enhanced properties. It is particularly useful in the synthesis of polymers and surfactants, where its properties can contribute to improved performance and functionality.
Used in Research and Development:
The availability of 1,1,1,3,3,3-hexafluoro-2-(2-iodo-5-methylphenyl)propan-2-ol in high purity grades makes it a valuable tool for research and development across various scientific fields. Its versatility and stability facilitate the exploration of new chemical reactions and the creation of innovative compounds.

Upstream product

• 1992-07-0 4-methyl-2-<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline 
• 106-49-0 p-toluidine 
• 69352-01-8 1-Chloro-1,3-dihydro-5-methyl-3,3-bis(trifluoromethyl)-1,2-benziodoxole 
• 187939-68-0 1-tert-butylperoxy-5-methyl-3,3-bistrifluoromethyl-1H-1,2-benziodoxole 
• 110-82-7 cyclohexane 

Downstream Products

• 1321992-75-9 (2-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-methylphenyl)trimethylstannane 
• 1321992-80-6 4-(bromomethyl)-2-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-1-iodobenzene 
• 1321992-81-7 N-allyl-N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-iodobenzyl)prop-2-en-1-amine 
• 1321992-82-8 N-allyl-N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)prop-2-en-1-amine 
• 1321992-83-9 (3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)phenyl)methanamine 
• 1321992-84-0 4-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzylamino)-4-oxobutanoic acid 
• 1321992-85-1 2,5-dioxopyrrolidin-1-yl 4-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzylamino)-4-oxobutanoate 
• 1321992-86-2 N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-iodobenzyl)-N-methylprop-2-en-1-amine 
• 1321992-87-3 N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)-N-methylprop-2-en-1-amine 
• 1321992-88-4 (3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)phenyl)-N-methylmethanamine 
• 1321992-89-5 4-((3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)(methyl)amino)-4-oxobutanoic acid 
• 1321992-90-8 2,5-dioxopyrrolidin-1-yl 4-((3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)(methyl)amino)-4-oxobutanoate 
• 1321992-91-9 3-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)-N-methylpropanamide 
• 1321992-92-0 N-(3-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-4-(tributylstannyl)benzyl)biotinamide 

Relevant articles and documents

HYPERVALENT RADIOACTIVE ASTATINE OR IODINE COMPOUNDS, AND PREPARATION METHODS THEREOF

The present invention relates to a compound having formula (I): wherein: - X is in particular 125I Or 211At; - R1 and R'1 are independently from each other chosen preferably from the group consisting of electron

Evidence for divalent iodine (9-I-2) radical intermediates in the thermolysis of (tert-butylperoxy)iodanes. An unusually efficient deiodination of o-iodocumyl alcohols by cyclohexyl radicals

1-(tert-Butylperoxy)-3,3-dimethyl-1H-1,2-benziodoxoles (2a and 2b) and 1-(tert-butylperoxy)-3,3-bis(trifluoromethyl)-5-methyl-1H-1,2-benziodo xole (2c) were prepared from chloroiodanes 1a-c and tert-butylhydroperoxide in the presence of potassium tert-butoxide in tetrahydrofuran. Products, kinetic data for the decomposition of 2 in cyclohexane, benzene, toluene, and acetonitrile (E(a) = 31.0 ± 1.0 kcal/mol, log A = 17.0 ± 0.5; 35-70 °C), and the increased rate of decomposition of 2c in benzene-d6 in the presence of a magnetic field (7 T) indicate that homolytic cleavage of the I-O bond in 2 with the formation of iodanyl (9-I-2) and tert-butylperoxyl radicals is the primary decomposition step. The nearly quantitative formation of iodocyclohexane during the decomposition of 2c in cyclohexane is due to the unexpected reaction of cyclohexyl radicals with 2-(2-iodo-5-methylphenyl)-1,1,1,3,3,3-hexafluoro-2-propanol, a primary decomposition product of 2c. The results of a separate study of the deiodination of o-iodocumyl alcohols (3) by cyclohexyl radicals are consistent with an S(H)2 type mechanism.