65671-47-8

Basic information

• Product Name: D-Glutamic acid, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-, 1-methyl 5-(phenylmethyl) ester
• CAS NO: 65671-47-8
• Molecular Formula: C21H30N2O7
• Molecular Weight: 422.478
• Mol File: 65671-47-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: D-Glutamic acid, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-, 1-methyl 5-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: D-Glutamic acid, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-, 1-methyl 5-(phenylmethyl) ester(65671-47-8)
• EPA Substance Registry System: D-Glutamic acid, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl]-, 1-methyl 5-(phenylmethyl) ester(65671-47-8)

Safety Data

• Hazardous Substances Data: 65671-47-8(Hazardous Substances Data)

Upstream product

• 53759-36-7 γ-benzyl tert-butoxycarbonyl-L-alanyl-D-glutamate 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 3392-05-0 Boc-Ala-O-N-hydroxysuccinimide 
• 2578-33-8 D-glutamic acid-5-benzyl ester 
• 15761-38-3 L-N-Boc-Ala 
• 57584-59-5 γ-OBzl-L-Glu-α-OMe 
• 1676-73-9 L-glutamic acid γ-benzyl ester 
• 100-51-6 benzyl alcohol 
• 41089-47-8 L-glutamic acid α-methyl γ-benzyl diester hydrochloride 

Downstream Products

• 77303-04-9 (S)-2-[(S)-2-((S)-4-Benzyloxycarbonyl-2-{(S)-2-[((S)-1-tert-butoxycarbonyl-pyrrolidine-2-carbonyl)-amino]-4-methyl-pentanoylamino}-butyrylamino)-propionylamino]-pentanedioic acid 5-benzyl ester 1-methyl ester 
• 77303-05-0 (S)-2-{(S)-2-[(S)-4-Benzyloxycarbonyl-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-butyrylamino]-propionylamino}-pentanedioic acid 5-benzyl ester 1-methyl ester 
• 77303-03-8 (S)-2-[(S)-2-((S)-4-Benzyloxycarbonyl-2-tert-butoxycarbonylamino-butyrylamino)-propionylamino]-pentanedioic acid 5-benzyl ester 1-methyl ester 
• 65671-48-9 (S)-2-((S)-2-Amino-propionylamino)-pentanedioic acid 5-benzyl ester 1-methyl ester; hydrochloride 

Relevant articles and documents

Tetrapeptide Copper Catalysts Capable Of Oxidizing Hydrocarbons At Room Temperature

The present invention relates to peptide copper catalysts capable of oxidizing hydrocarbons at room temperature.

Synthesis of Peptide Analogues of Prothrombin Precursor Sequence 5-9. Substrate Specificity of Vitamin K Dependent Carboxylase

Thirty-five analogues of Phe-Leu-Glu-Glu-Leu, the pentapeptide sequence 5-9 of bovine prothrombin precursor, were synthesized and assayed as potential substrates or inhibitors of rat liver vitamin K dependent carboxylase.Carboxylation of substrate was determined by measuring the incorporation of carbon-14 labeled bicarbonate into product.Changes in substrate carboxylation produced by changing peptide chain length, amino acid chirality, or the distance seperating the peptide chain backbone from the carboxyl group were measured.The data suggest that the carboxylase carboxylates L-glutamic acid residues and does not carboxylate L-aspartic acid, L-homoglutamic acid, glutamine, or D-glutamic acid residues; tri- through pentapeptides are better substrates than mono- or bis(amino acid) derivatives, and hydrophobic groups added to the N-terminus can produce better substrates for the enzyme.None of the synthetic substrates is carboxylated as effectively as the endogenous protein substrates for the enzyme.The effect of structure on additional parameters affecting carboxylation is discussed.