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BOC-LYS(ME)2-OH, also known as N-(tert-butoxycarbonyl)-N,N-dimethyl-L-lysine, is a synthetic amino acid derivative with a protected side chain. It is characterized by the presence of a tert-butoxycarbonyl (BOC) group and two methyl (Me) groups on the side chain, which provide stability and reactivity in various chemical reactions.

65671-53-6

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65671-53-6 Usage

Uses

Used in Pharmaceutical Industry:
BOC-LYS(ME)2-OH is used as a key intermediate in the synthesis of peptidyl α-keto thiazoles, which serve as tissue factor VIIa inhibitors. These inhibitors play a crucial role in the development of therapeutic agents for the treatment of coagulation disorders and related conditions.
Additionally, BOC-LYS(ME)2-OH is utilized in the preparation of tetrahydropyranylglycine sulfonamides, which act as bradykinin hB2 receptor antagonists. These antagonists are valuable in the research and development of drugs targeting the bradykinin pathway, which is involved in various physiological processes, including pain, inflammation, and blood pressure regulation.

Check Digit Verification of cas no

The CAS Registry Mumber 65671-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,7 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65671-53:
(7*6)+(6*5)+(5*6)+(4*7)+(3*1)+(2*5)+(1*3)=146
146 % 10 = 6
So 65671-53-6 is a valid CAS Registry Number.

65671-53-6 Well-known Company Product Price

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  • Alfa Aesar

  • (H52437)  N(alpha)-Boc-N(epsilon),N(epsilon)-dimethyl-L-lysine, 97%   

  • 65671-53-6

  • 250mg

  • 882.0CNY

  • Detail

  • Alfa Aesar

  • (H52437)  N(alpha)-Boc-N(epsilon),N(epsilon)-dimethyl-L-lysine, 97%   

  • 65671-53-6

  • 1g

  • 2646.0CNY

  • Detail

65671-53-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-6-(dimethylamino)-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid

1.2 Other means of identification

Product number -
Other names N-[(tert-Butoxy)carbonyl]-N',N'-dimethyl-L-lysine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65671-53-6 SDS

65671-53-6Relevant academic research and scientific papers

ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION OF BRM AND METHODS THEREOF

-

Page/Page column 224, (2022/02/05)

The subject matter described herein is directed to antibody-CIDE conjugates (Ab-CIDEs) that target BRM for degradation, to pharmaceutical compositions containing them, and to their use in treating diseases and conditions where BRM degradation is beneficial.

COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE

-

Paragraph 0886, (2021/10/02)

The invention provides compounds that are inhibitors of the protein embryonic ectoderm development (EED), pharmaceutical compositions, their use in modulating the activity of EED, and their use in the treatment of medical disorders, such as cancer. The invention further provides methods of treating medical disorders, such as cancer, and covalently modifying and/or modulating the activity of EED, using an agent that reacts with, and forms a covalent bond to, cysteine324 of EED.

Development of a fluorogenic probe with a transesterification switch for detection of histone deacetylase activity

Baba, Reisuke,Hori, Yuichiro,Mizukami, Shin,Kikuchi, Kazuya

supporting information, p. 14310 - 14313 (2012/11/07)

Histone deacetylases (HDACs) are key enzymatic regulators of many cellular processes such as gene expression, cell cycle, and tumorigenesis. These enzymes are attractive targets for drug development. However, very few simple methods for monitoring HDAC ac

Quinazoline derivatives useful in cancer treatment

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Page/Page column 223-224, (2010/11/25)

The present invention provides compounds of Formula I (wherein R1, R2, R3, L, and X are as defined herein). [image] or a pharmaceutically acceptable salt, solvate or ester thereof. The present invention also provides compositions comprising these compound

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