656799-87-0Relevant academic research and scientific papers
Kinetic Resolution of Allylic Alcohol with Chiral BINOL-Based Alkoxides: A Combination of Experimental and Theoretical Studies
Liu, Yidong,Liu, Song,Li, Dongmei,Zhang, Nan,Peng, Lei,Ao, Jun,Song, Choong Eui,Lan, Yu,Yan, Hailong
supporting information, p. 1150 - 1159 (2019/01/11)
The development and characterization of enantioselective catalytic kinetic resolution of allylic alcohols through asymmetric isomerization with chiral BINOL derivatives-based alkoxides as bifunctional Br?nsted base catalysts were described in the study. A number of chiral BINOL derivatives-based alkoxides were synthesized, and their structure-enantioselectivity correlation study in asymmetric isomerization identified a promising chiral Br?nsted base catalyst, which afforded various chiral secondary allylic alcohols (ee up to 99%, S factor up to >200). In the mechanistic study, alkoxide species were identified as active species and the phenol group of BINOL largely affected the high reactivity and enantioselectivity via hydrogen bonding between the chiral Br?nsted base catalyst and substrates. The strategy is the first successful synthesis strategy of various chiral secondary allylic alcohols through enantioselective transition-metal-free base-catalyzed isomerization. The applicability of the strategy had been demonstrated by the synthesis of the bioactive natural product (+)-veraguensin.
A method of synthesizing chiral alkene propyl alcohol
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Paragraph 0025; 0032-0034, (2019/07/04)
The invention discloses a method for synthesizing chiral alkene propyl alcohol method, which belongs to the technical field of organic chemistry. The method adopts the [...] derived binaphthol potassium salt as a chiral [...] catalyst, catalytic [...] pro
Stereochemistry for engineering spin crossover: Structures and magnetic properties of a homochiral vs. racemic [Fe(N3O2)(CN)2] complex
Wang, Qiang,Venneri, Shari,Zarrabi, Niloofar,Wang, Hongfeng,Desplanches, Cédric,Létard, Jean-Fran?ois,Seda, Takele,Pilkington, Melanie
, p. 6711 - 6714 (2015/04/14)
The Schiff-base condensation of the R,R-(+)-diamine (2a) with 2,6-diacetyl pyridine in the presence of FeII affords the macrocyclic complex [Fe(dpN3O2)(CN)2] (3a) (dp = diphenyl) with ligand centred chirality co
Modular chiral polyether podands and their lanthanide complexes
Aspinall, Helen C.,Greeves, Nicholas,McIver, Edward G.
, p. 10453 - 10463 (2007/10/03)
A novel series of modular chiral polyether podands derived from enantiomerically pure hydrobenzoin and binaphthol has been prepared using a NaH/15-crown-5 mediated Williamson ether synthesis. These new homochiral ligands form catalytically active complexes with lanthanide triflates, two of which have been characterised by X-ray diffraction.
