6568-93-0

Upstream product

• 31787-00-5 7-acetylamino-4-methyl-3-phenyl-coumarin 
• 26093-31-2 7-amino-4-methylcoumarin. 
• 98-80-6 phenylboronic acid 
• 114-70-5 sodium phenylacetate 
• 40547-58-8 N-(4-acetyl-3-hydroxyphenyl)acetamide 

Downstream Products

• 92794-25-7 7-chloro-4-methyl-3-phenyl-chromen-2-one 
• 92796-41-3 7-bromo-4-methyl-3-phenyl-coumarin 
• 92795-06-7 7-iodo-4-methyl-3-phenyl-coumarin 
• 101973-12-0 4-Methyl-N-(4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl)-benzenesulfonamide 
• 101973-16-4 4,8-Dimethyl-3-phenyl-7-(toluene-4-sulfonyl)-8,9-dihydro-7H-pyrano[2,3-e]indol-2-one 
• 101973-13-1 N-Allyl-4-methyl-N-(4-methyl-2-oxo-3-phenyl-2H-chromen-7-yl)-benzenesulfonamide 
• 119021-00-0 4,8-Dimethyl-3-phenyl-8,9-dihydro-7H-pyrano[2,3-e]indol-2-one 

Relevant academic research and scientific papers

KMnO4/AcOH-mediated C3-selective direct arylation of coumarins with arylboronic acids

An efficient protocol for KMnO4/AcOH-mediated dehydrogenative direct radical arylation of coumarins with arylboronic acids to afford 3-arylcoumarin derivatives is described. A similar reaction system is also applicable to the 3-arylation of quinolinone derivatives. These KMnO4/AcOH-mediated coupling reactions occur regioselectively at the C3 position of coumarins and quinolinones. Some notable features of this method are high efficiency, moderate to good yield, and a broad group tolerance.