656808-43-4Relevant academic research and scientific papers
Synthesis and structure-activity relationships of novel anti-hepatitis C agents: N3,5′-cyclo-4-(β-D-ribofuranosyl)-vic-triazolo[4, 5-b]pyridin-5-one derivatives
Wang, Peiyuan,Du, Jinfa,Rachakonda, Suguna,Chun, Byoung-Kwon,Tharnish, Phillip M.,Stuyver, Lieven J.,Otto, Michael J.,Schinazi, Raymond F.,Watanabe, Kyoichi A.
, p. 6454 - 6460 (2007/10/03)
Several 6- and 7-monosubstituted N3,5′-cyclo-4-(β-D- ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one derivatives as well as the 5-thiono analogue were synthesized, providing structure - anti-hepatitis C virus (HCV) activity relationships for th
Synthesis of N3,5′-cyclo-4-(β-D-ribofuranosyl)-vic- triazolo[4,5-b]pyridin-5-one and its 3′-deoxysugar analogue as potential anti-hepatitis C virus agents
Wang, Peiyuan,Hollecker, Laurent,Pankiewicz, Krzysztof W.,Patterson, Steven E.,Whitaker, Tony,McBrayer, Tamara R.,Tharnish, Phillip M.,Stuyver, Lieven J.,Schinazi, Raymond F.,Otto, Michael J.,Watanabe, Kyoichi A.
, p. 957 - 960 (2007/10/03)
We recently discovered a novel compound, identified as N 3,5′-cyclo-4-(β-D-ribofuranosyl)-vic-triazolo[4,5-b] pyridinin-5-one, with anti-hepatitis C virus (HCV) activity in vitro. The structure was confirmed by chemical synthesis from 2-hydroxy
Synthesis of N3,5′-cyclo-4-(β-D-ribofuranosyl)-vic- triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity
Wang, Peiyuan,Hollecker, Laurent,Pankiewicz, Krzysztof W.,Patterson, Steven E.,Whitaker, Tony,McBrayer, Tamara R.,Tharnish, Phillip M.,Sidwell, Robert W.,Stuyver, Lieven J.,Otto, Michael J.,Schinazi, Raymond F.,Watanabe, Kyoichi A.
, p. 6100 - 6103 (2007/10/03)
A novel anti-hepatitis C virus (HCV) agent, N3,5′-cyclo-4- (β-D-ribofuranosyl)-vic-triazolo(4,5-b]pyridinin-5-one, was identified, and the structure was confirmed by chemical synthesis from 2-hydroxy-5- nitropyridine.
