656824-47-4

Upstream product

• 66192-25-4 2-bromo-5-methoxybenzyl chloride 
• 656824-48-5 (+)-2-((1S,7aS)-1-tert-butoxy-7a-methyl-2,3,7,7a-tetrahydro-1H-inden-4-yl)-5,5-dimethyl-[1,3,2]dioxaborinane 
• 41878-38-0 (1S,7aS)-1-tert-butoxy-7a-methyl-1,2,3,6,7,7a-hexahydro-5H-inden-5-one 
• 656824-51-0 (+)-dithiocarbonic acid O-((1S,5S,7aS)-4-bromo-1-tert-butoxy-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-inden-5-yl) ester S-methyl ester 
• 656824-50-9 (-)-(1S,5S,7aS)-4-bromo-1-tert-butoxy-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-inden-5-ol 
• 656824-49-6 (-)-(1S,7aS)-4-bromo-1-tert-butoxy-7a-methyl-1,2,3,6,7,7a-hexahydro-inden-5-one 
• 656824-52-1 (+)-(1S,7aS)-4-bromo-1-tert-butoxy-7a-methyl-2,3,7,7a-tetrahydro-1H-indene 

Relevant academic research and scientific papers

Synthesis of enantiopure B-nor-steroids by multiple Pd-catalyzed transformations

The synthesis of the novel enantiopure B-nor-steroid 9 is described employing a combination of a Suzuki- and a Heck-reaction. As substrates the 2-bromobenzylchloride (11) and the boronic ester 16 were used; the latter was prepared from the Hajos-Wiechert