656827-17-7

Upstream product

• 501-53-1 benzyl chloroformate 
• 656827-16-6 (1S)-1-[(4R)-3-N-benzyloxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl]-but-3-en-1-ol 
• 656827-14-4 1-[(4R)-3-N-benzyloxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl]-but-3-en-1-one 
• 656827-13-3 (R)-benzyl-4-(methoxy(methyl)carbamoyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 1092473-80-7 (R)-benzyl 3-hydroxy-1-(methoxy(methyl)amino)-1-oxopropane-2-ylcarbamate 
• 6081-61-4 N-(benzyloxycarbonyl)-D-serine 
• 656827-11-1 (4S,5R)-5-(benzyloxycarbonyl)amino-2,2-dimethyl-4-(2-propenyl)-1,3-dioxane 

Downstream Products

• 1450984-45-8 (2R,3S)-2-((benzoxycarbonyl)amino)-1-[(tert-butyldimethylsilyl)oxy]hex-5-en-3-yl acetate 
• 1450984-49-2 benzyl (2R,3S,5S)-3-hydroxy-2-hydroxymethyl-5-(iodomethyl)pyrrolidine-1-carboxylate 
• 337975-50-5 benzyl (2R,3S,5S)-3-acetoxy-2-((tert-butyldimethylsilyloxy)methyl)-5-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 337975-48-1 benzyl (2S,4S,5R)-4-acetoxy-2-carboxy-5-[(tert-butyldimethylsilyloxy)methyl]pyrrolidine-1-carboxylate 
• 1450984-46-9 C₂₆H₃₆N₂O₉Si 
• 1450984-47-0 benzyl (2R,3S,5S)-3-acetoxy-5-((dibenzyloxyphosphoryloxy)methyl)-2-((tert-butyldimethylsilyloxy)methyl)pyrrolidine-1-carboxylate 
• 95863-88-0 (2S,4S,5R)-4-Hydroxy-5-hydroxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 
• 1450984-48-1 C₂₈H₃₂NO₈P 
• 95863-87-9 (2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)pyrrolidine-2-carboxylic acid 
• 1450984-51-6 C₁₈H₂₂INO₆ 
• 132592-32-6 (5R,4S,2S)-4-hydroxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester 

Relevant academic research and scientific papers

Polyhydroxylated pyrrolidine and 2-oxapyrrolizidine as glycosidase inhibitors

Using D-serine as a chiral precursor, a polyhydroxylated pyrrolidine (1), its derivatives bearing carboxylate, phosphate and phosphonate groups (2-4) and an oxapyrrolizidine (5) were synthesized. The pyrrolidine ring was formed by intramolecular amino-mercuration. The bicyclic scaffold of oxapyrrolizidine was further constructed by an intramolecular attack of the carbamate group on the iodomethyl group. Compounds 1 and 5 were found to inhibit β-glucosidase and α-galactosidase, respectively, in a competitive manner, whereas compounds 2, 3 and 4 did not produce significant inhibition against glycosidases. The Royal Society of Chemistry 2013.

Trimethylsilyl trifluoromethanesulfonate (TMSOTf) assisted facile deprotection of N,O-acetonides

(Chemical Equation Presented) Employing TMSOTf as an easily available reagent, we have developed a mild and efficient method for the deprotection of both terminal and internal N,O-acetonide functionalities. Various regularly used protecting groups and com

An Efficient and Highly Stereocontrolled Route to Bulgecinine Hydrochloride

(-)-Bulgecinine is a nonproteinogenic amino acid component present in bulgecins A, B, and C, antibiotic glycopeptides derived from Pseudomonas acidophila and Pseudomonas mesoacidophila. In combination with β-lactam antibiotics, bulgecins exihibit a unique