656827-19-9

Upstream product

• 501-53-1 benzyl chloroformate 
• 656827-16-6 (1S)-1-[(4R)-3-N-benzyloxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl]-but-3-en-1-ol 
• 656827-14-4 1-[(4R)-3-N-benzyloxycarbonyl-2,2-dimethyl-1,3-oxazolidin-4-yl]-but-3-en-1-one 
• 656827-13-3 (R)-benzyl-4-(methoxy(methyl)carbamoyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 1092473-80-7 (R)-benzyl 3-hydroxy-1-(methoxy(methyl)amino)-1-oxopropane-2-ylcarbamate 
• 6081-61-4 N-(benzyloxycarbonyl)-D-serine 
• 1321980-70-4 C₂₄H₃₁N₃O₅ 
• 1321980-74-8 C₉H₁₇NO₃ 
• 1321980-73-7 (4aR,6S,7aS)-6-(benzyloxymethyl)-2,2-dimethylhexahydro[1,3]dioxino[5,4-b]pyrrole 
• 1321980-72-6 C₁₇H₂₅N₃O₆S 
• 1321980-71-5 C₁₆H₂₃N₃O₄ 
• 1321980-67-9 2-azido-6-(benzyloxy)-5-(4-methoxybenzyloxy)hexane-1,3-diol 
• 1321980-64-6 (3-{3-(benzyloxy)-2-[(4-methoxybenzyl)oxy]propyl}oxiran-2-yl)methanol 
• 1321980-63-5 C₂₁H₂₆O₄ 

Downstream Products

• 656827-21-3 methyl (4aR,6S,7aS)-5-benzyloxycarbonyl-2,2-dimethylhexahydro[1,3]dioxino[5,4-b]pyrrol-6-carboxylate 

Relevant academic research and scientific papers

Polyhydroxylated pyrrolidine and 2-oxapyrrolizidine as glycosidase inhibitors

Using D-serine as a chiral precursor, a polyhydroxylated pyrrolidine (1), its derivatives bearing carboxylate, phosphate and phosphonate groups (2-4) and an oxapyrrolizidine (5) were synthesized. The pyrrolidine ring was formed by intramolecular amino-mercuration. The bicyclic scaffold of oxapyrrolizidine was further constructed by an intramolecular attack of the carbamate group on the iodomethyl group. Compounds 1 and 5 were found to inhibit β-glucosidase and α-galactosidase, respectively, in a competitive manner, whereas compounds 2, 3 and 4 did not produce significant inhibition against glycosidases. The Royal Society of Chemistry 2013.

Highly diastereoselective construction of substituted pyrrolidines: Formal synthesis of (-)-bulgecinine

A highly diastereoselective synthesis of substituted pyrrolidines has been achieved starting from nonchiral molecule, allyl bromide, or cis-but-2-ene-1,4-diol. The method involves the asymmetric epoxidation and endo-mode epoxide opening with azide nucleop

An Efficient and Highly Stereocontrolled Route to Bulgecinine Hydrochloride

(-)-Bulgecinine is a nonproteinogenic amino acid component present in bulgecins A, B, and C, antibiotic glycopeptides derived from Pseudomonas acidophila and Pseudomonas mesoacidophila. In combination with β-lactam antibiotics, bulgecins exihibit a unique