65685-55-4 Usage
Uses
Used in Pharmaceutical Industry:
1,2-Benzisoxazol-6-ol is used as a key intermediate in the synthesis of drugs with psychotropic and neuroleptic properties, contributing to the development of medications for mental health disorders.
Used in Organic Electronics:
1,2-Benzisoxazol-6-ol serves as a versatile building block for the synthesis of functional organic materials, playing a crucial role in the advancement of organic electronic devices.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, 1,2-Benzisoxazol-6-ol is studied for its potential use in developing new therapeutic agents to combat microbial infections.
Used in Antidiabetic Applications:
1,2-Benzisoxazol-6-ol has been investigated for its antidiabetic properties, indicating its potential in the development of treatments for diabetes management.
However, it is essential to handle and use 1,2-Benzisoxazol-6-ol with caution, as it may pose harmful effects on human health and the environment if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 65685-55-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,8 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 65685-55:
(7*6)+(6*5)+(5*6)+(4*8)+(3*5)+(2*5)+(1*5)=164
164 % 10 = 4
So 65685-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NO2/c9-6-2-1-5-4-8-10-7(5)3-6/h1-4,9H
65685-55-4Relevant academic research and scientific papers
Triflic anhydride: A mild reagent for highly efficient synthesis of 1,2-benzisoxazoles, isoxazolo, and isothiazolo quinolines without additive or base
Kalkhambkar, Rajesh G.,Yuvaraj
supporting information, p. 547 - 555 (2014/01/23)
The synthetic utility of trifluoromethanesulphonic anhydride (triflic anhydride, TA) without additive or base for the high-yielding synthesis of a wide variety of 1,2-benzisoxazoles from 2-hydroxyaryl aldoximes and ketoximes under mild conditions has been carried out for the first time. As a continuation of our study, syntheses of isoxazolo and isothiazolo quinolones have also been demonstrated using triflic anhydride under similar conditions. This method is simple and has benefits from the easy way to isolate the products in excellent yields.
A novel method for the highly efficient synthesis of 1,2-benzisoxazoles under neutral conditions using the Ph3P/DDQ system
Iranpoor, Nasser,Firouzabadi, Habib,Nowrouzi, Najmeh
, p. 8247 - 8250 (2007/10/03)
The use of Ph3P/DDQ offers a novel, neutral and highly efficient method for the efficient conversion of 2-hydroxyaryl aldoximes and ketoximes to 1,2-benzisoxazoles in excellent yields at room temperature.
