65686-77-3 Usage
Uses
Used in Pharmaceutical Industry:
2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE is used as a key intermediate in the synthesis of various drugs for treating a wide range of conditions, including psychiatric disorders and neurological diseases. Its unique structure and reactivity contribute to the development of effective medications that address these health issues.
Used in Organic Chemistry:
In the field of organic chemistry, 2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE is utilized for its reactivity and ability to participate in various chemical reactions. This property makes it a valuable compound for researchers and chemists working on the development of new chemical processes and products.
Used in Research and Industrial Applications:
The hydrochloride form of 2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE HYDROCHLORIDE is commonly used in research and industrial applications due to its stability and ease of handling. Its stable nature allows for more efficient and reliable experimentation, making it a preferred choice for scientists and professionals in the industry.
Check Digit Verification of cas no
The CAS Registry Mumber 65686-77-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,8 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65686-77:
(7*6)+(6*5)+(5*6)+(4*8)+(3*6)+(2*7)+(1*7)=173
173 % 10 = 3
So 65686-77-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3NO.ClH/c1-14-7-4-2-6(3-5-7)8(13)9(10,11)12;/h2-5,8H,13H2,1H3;1H
65686-77-3Relevant academic research and scientific papers
Thermocontrolled benzylimine-benzaldimine rearrangement over Nafion-H catalysts for efficient entry into α-trifluoromethylbenzylamines
Prakash, G.K. Surya,Glinton, Kevin E.,Panja, Chiradeep,Gurung, Laxman,Battamack, Patrice T.,T?r?k, Béla,Mathew, Thomas,Olah, George A.
experimental part, p. 607 - 611 (2012/02/13)
Nafion-H and Nafion SAC-13 are efficient solid Br?nsted acid catalysts for the preparation of trifluoromethyl ketimines from benzylamines and trifluoromethylated ketones in high yields. A finely tuned benzylimine- benzaldimine rearrangement by facile 1,3-hydrogen shift has been achieved for the formation of fluorinated benzaldimines in high yields by careful optimization of reaction conditions including attempts under microwave conditions and a flow system. These α-trifluoromethylated benzaldimines are efficient precursors for pharmaceutically important α- trifluoromethylated benzylamines, accessed through their direct acid hydrolysis.
