65689-48-7

Basic information

• Product Name: L-Phenylalanine, 1-[(1,1-dimethylethoxy)carbonyl]-L-prolyl-, ethyl ester
• CAS NO: 65689-48-7
• Molecular Formula: C21H30N2O5
• Molecular Weight: 390.48
• Mol File: 65689-48-7.mol

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, 1-[(1,1-dimethylethoxy)carbonyl]-L-prolyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, 1-[(1,1-dimethylethoxy)carbonyl]-L-prolyl-, ethyl ester(65689-48-7)
• EPA Substance Registry System: L-Phenylalanine, 1-[(1,1-dimethylethoxy)carbonyl]-L-prolyl-, ethyl ester(65689-48-7)

Safety Data

• Hazardous Substances Data: 65689-48-7(Hazardous Substances Data)

Upstream product

• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 3182-93-2 (L)-phenylalanine ethyl ester hydrochloride 

Relevant articles and documents

Amide and Peptide Bond Formation in Water at Room Temperature

A general and environmentally responsible method for the formation of amide/peptide bonds in an aqueous micellar medium is described. Use of uronium salt (1-cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium hexafluorophosphate (COMU) as a coupling reagent, 2,6-lutidine, and TPGS-750-M represents mild conditions associated with these valuable types of couplings. The aqueous reaction medium is recyclable leading to low E Factors.