65690-71-3

Basic information

• Product Name: Benzenepropanamide, N-hydroxy-N-phenyl-
• CAS NO: 65690-71-3
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol File: 65690-71-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, N-hydroxy-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-hydroxy-N-phenyl-(65690-71-3)
• EPA Substance Registry System: Benzenepropanamide, N-hydroxy-N-phenyl-(65690-71-3)

Safety Data

• Hazardous Substances Data: 65690-71-3(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 586-96-9 Nitrosobenzene 
• 112403-88-0 O-methyl N-phenyl-3-phenylpropanohydroxamate 

Downstream Products

• 67176-93-6 1-phenyl-1,2,3,4-tetrahydroquinolin-2-one 
• 152189-81-6 N-(4-chlorophenyl)-3-phenylpropanamide 
• 152189-79-2 N-(2-chlorophenyl)-3-phenylpropanamide 
• 152189-75-8 N-(2-hydroxyphenyl)-3-phenylpropanamide 

Relevant articles and documents

N-heterocyclic-carbene-catalyzed one-pot synthesis of hydroxamic esters

The honey pot: The NHC-catalyzed reaction between nitrosobenzenes, aromatic/aliphatic aldehydes, and enals proceeded through an aza-benzoin-type reaction and an internal redox esterification to afford hydroxamic esters in good yields. Copyright

N-heterocyclic carbene (NHC)-catalyzed direct amidation of aldehydes with nitroso compounds

(Chemical Equation Presented) NHC-catalyzed direct amidation of aldehydes with nitroso compounds is a powerful method for the synthesis of N-arylhydroxamic acids. A variety of aryl, alkyl, alkenyl, and heterocyclic aldehydes were found to give excellent yields of the corresponding N-arylhydroxamic acids. This chemistry was also extended to the synthesis of chiral N-arylhydroxamic acids by kinetic resolution of α-branched aldehydes, a domino amidation-redox amination reaction of acrolein, and a three-component reaction for the synthesis of N-arylaziridines.