65693-78-9Relevant articles and documents
METHOD FOR PRODUCING AN N-(1-ARYL-ALK-1-ENYL)-ACETAMIDE OR N-(1-HETEROARYL-ALK-1-ENYL)-ACETAMIDE
-
Page/Page column 20-21, (2008/06/13)
The invention relates to a method for producing an N-(1-aryl-alk-1-enyl)-acetamide or N-(1-heteroaryl-alk-1-enyl)-acetamide. According to the invention, an N-(alk-1-enyl)-acetamide is reacted with an aryl- or heteroaryl-chloride, bromide, iodide or triflate in the presence of a) a Pd-catalyst and b) water and/or an ionic liquid, and c) dimethylformamide (DMF), N,N-dimethylacetamide (DMAC) and/or surplus N-(alk-1-enyl)-acetamide.