65696-19-7

Basic information

• Product Name: Benzoic acid, 2-[(3-oxo-1-propenyl)thio]-, methyl ester, (E)-
• CAS NO: 65696-19-7
• Molecular Formula: C11H10O3S
• Molecular Weight: 222.265
• Mol File: 65696-19-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(3-oxo-1-propenyl)thio]-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(3-oxo-1-propenyl)thio]-, methyl ester, (E)-(65696-19-7)
• EPA Substance Registry System: Benzoic acid, 2-[(3-oxo-1-propenyl)thio]-, methyl ester, (E)-(65696-19-7)

Safety Data

• Hazardous Substances Data: 65696-19-7(Hazardous Substances Data)

Upstream product

• 624-67-9 Propargylic aldehyde 
• 4892-02-8 Methyl thiosalicylate 

Downstream Products

• 125198-01-8 methyl (1E,3Z)-2-(1,3-pentadecadien-6-ynylthio)benzoate 
• 125197-88-8 methyl (1E,3Z,6Z)-2-(1,3,6-pentadecatrienylthio)benzoate 

Relevant articles and documents

Design, Synthesis, and 5-Lipoxygenase-Inhibiting Properties of 1-Thio-Substiuted Butadienes

The synthesis of novel 1-thio-substituted butadienes, designed as mechanism-based 5-lipoxygenase inhibitors, is described.The structure of these compounds closely resembles a proposed high-energy intermediate during the lipoxygenation of arachidonic acid.They demonstrate 5-lipoxygenase inhibition in vitro and in vivo.The most potent compound is 15a with an IC50 of μM in vitro.LTC4 release was inhibited by 80percent after intraperitoneal administration of 15c at a dose of 2 mg/kg.