65700-70-1Relevant academic research and scientific papers
Novel bivalent ligands carrying potential antinociceptive effects by targeting putative mu opioid receptor and chemokine receptor CXCR4 heterodimers
Li, Mengchu,Ma, Hongguang,Nassehi, Nima,Pagare, Piyusha P.,Santos, Edna J.,Selley, Dana E.,Stevens Negus, S.,Wang, Huiqun,Zhang, Yan
, (2022/02/01)
The functional interactions between opioid and chemokine receptors have been implicated in the pathological process of chronic pain. Mounting studies have indicated the possibility that a MOR-CXCR4 heterodimer may be involved in nociception and related ph
A METHOD FOR THE N-DEMETHYLATION OF N-METHYL HETEROCYCLES
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, (2011/04/19)
The present invention provides methods of N-demethylating, N-methylated heterocycles and N-methyl, N-oxide heterocycles using a transition metal with an oxidation state of zero, ferrocene or substituted derivatives thereof, or Cr 3+ .N-demethylated heterocycles prepared by the methods of the present invention are also provided.
