65715-48-2

Basic information

• Product Name: Benzoic acid, 4-(4-methyl-1-piperazinyl)-3-nitro-, methyl ester
• Synonyms: HMS2647P05;4-(4-methyl-piperazin-1-yl)-3-nitro-benzoic acid methyl ester;methyl 4-(4-methyl-1-piperazinyl)-3-nitrobenzoate
• CAS NO: 65715-48-2
• Molecular Formula: C13H17N3O4
• Molecular Weight: 279.296
• Mol File: 65715-48-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(4-methyl-1-piperazinyl)-3-nitro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(4-methyl-1-piperazinyl)-3-nitro-, methyl ester(65715-48-2)
• EPA Substance Registry System: Benzoic acid, 4-(4-methyl-1-piperazinyl)-3-nitro-, methyl ester(65715-48-2)

Safety Data

• Hazardous Substances Data: 65715-48-2(Hazardous Substances Data)

Upstream product

• 400-94-2 4-fluoro-3-nitrobenzoyl chloride 
• 453-71-4 3-nitro-4-fluorobenzoic acid 
• 109-01-3 1-methyl-piperazine 
• 329-59-9 4-fluoro-3-nitro-benzoic acid methyl ester 

Downstream Products

• 65639-61-4 methyl 3-amino-4-(4-methylpiperazin-1-yl) benzoate 
• 948018-56-2 4-(4-methyl-piperazin-1-yl)-3-nitro-benzoic acid hydrochloride 

Relevant articles and documents

Structure-based design of ester compounds to inhibit MLL complex catalytic activity by targeting mixed lineage leukemia 1 (MLL1)–WDR5 interaction

WDR5 is an essential protein for enzymatic activity of MLL1. Targeting the protein–protein interaction (PPI) between MLL1 and WDR5 represents a new potential therapeutic strategy for MLL leukemia. Based on the structure of reported inhibitor WDR5-0103, a