65734-62-5

Upstream product

• 50816-19-8 8-bromooctanol 
• 603-35-0 triphenylphosphine 

Downstream Products

• 33956-49-9 (8E,10E)-dodeca-8,10-dienol 
• 28079-04-1 (Z)-8-dodecen-1-yl acetate 
• 38363-29-0 (E)-8-dodecenyl acetate 
• 35835-80-4 (Z)-8-tetradecenyl acetate 
• 56218-64-5 (E)-8-tetradecenyl acetate 
• 54897-69-7 (E/Z)-8-Tetradecen-1-yl acetate 
• 1581234-53-8 triphenyl(8-((3,4,5-trihydroxybenzoyl)oxy)octyl)phosphonium bromide 
• 1026604-38-5 4-[9-(2,4-Dichloro-phenyl)-nonylsulfanyl]-3-oxo-butyric acid methyl ester 
• 154566-20-8 9-(2,4-dichlorophenyl)-1-nonanol 
• 269725-97-5 4-azido-2,3,5,6-tetrafluorobenzyl 6-((2R)-6-{[tert-butyl(dimethyl)silyl]oxy}-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)nonyl ether 
• 743427-12-5 toluene-4-sulfonic acid 9-(5-methyl-furan-2-yl)-nonyl ester 
• 180622-58-6 9-(2,4-dichlorophenyl)-8-nonen-1-ol 
• 40642-40-8 (Z)-8-dodecenol 
• 42513-42-8 E₈,E₁₀-dodecadien-1-ol 

Relevant academic research and scientific papers

Antiproliferative and uncoupling effects of delocalized, lipophilic, cationic gallic acid derivatives on cancer cell lines. Validation in vivo in singenic mice

Tumor cells principally exhibit increased mitochondrial transmembrane potential (Δψm) and altered metabolic pathways. The therapeutic targeting and delivery of anticancer drugs to the mitochondria might improve treatment efficacy. Gallic acid e

ABSOLUTE CONFIGURATIONS OF 9,10-EPOXYDODECANOIC ACIDS BIOSYNTHESIZED BY MICROSOMES FROM JERUSALEM ARTICHOKE TUBERS

9Z- and 9E-Dodecenoic acids were epoxidized by a microsome preparation from Jerusalem artichoke tuber to form cis- and trans-epoxydodecanoic acids, respectively.Steric analysis showed that (a) 78percent of the cis-9,10-epoxydodecanoic acid had the 9R,10S configuration and 22percent had the 9S,10R configuration and that (b) 57percent of the trans-9,10-epoxydodecanoic acid had the 9S,10S configuration and 43percent had the 9R,10R configuration.

Compound, antibacterial finishing liquid, and preparation method and application of compound

The invention provides a compound, antibacterial finishing liquid, and a preparation method and application of the compound. The general formula of the compound is shown in the description. The R1 ishalogen; the R2 is halogen, hydrogen, nitryl or heteroat

Microwave and ultrasound assisted synthesis of 16-methyl-8(Z)-heptadecenoic and 16-methyl-6(Z)-heptadecenoic acids

The first total synthesis of two novel iso-branched heptadecenoic acids, the major components in a species of bacterium, Micrococcus, has been carried out using a rapid, simple and clean process utilizing microwave and ultrasound radiations.

Phosphonioalkylthiosulfate zwitterions - New masked thiol ligands for the formation of cationic functionalised gold nanoparticles

We report the synthesis and structural characterisation of a new family of stable phosphonioalkylthiosulfate zwitterions, R3P +(CH2)nS2O3- (R = Ph or Bu, n = 3,4,6, 8 or 10) which behave as cationic masked thiolate ligands with applications in the functionalisation of gold nanoparticles, having potential as new diagnostic biorecognition systems. The ligands were prepared by treatment of ω-bromoalkylphosphonium salts with sodium thiosulfate. The crystal and molecular structures of the zwitterions (R = Ph, n = 3) and (R = Bu, n = 3) were determined. A series of phosphonioalkanethiolate-capped gold nanoparticles dispersed in water was prepared by borohydride reduction of potassium tetrachloroaurate in the presence of the zwitterions in a dichloromethane-water system. UV-visible spectroscopy and scanning transmission electron-microscopy indicated that capped nanoparticles of ca. 5 nm diameter were present. The Royal Society of Chemistry 2006.

Synthesis of phytyl- and chroman-derivatized photoaffinity labels based on α-tocopherol

Photoaffinity analogues of α-tocopherol have been prepared by substituting photosensitive functional groups at either the terminus of an alkyl chain of varying length mimicking the phytyl tail or on C-3 of the chroman portion of tocopherol. The alkyl chain-modified compounds 2a-d contain a hexyl to nonyl alkyl chain extending from C-2 of the chroman, terminating in a tetrafluoroazidobenzyloxy group. These compounds were prepared starting from the commercially available Trolox acid 4, followed by esterification, protection, and reduction to the silyl-protected Trolox aldehyde 7, which was coupled using Wittig chemistry to different ω- hydroxyphosphonium bromides. Reduction of the alkene product, coupling with p-azidotetrafluorobenzyl bromide, and deprotection of the phenolic silyl group gave compounds 2a-d in excellent yields. Chroman-functionalized photoaffinity labels were synthesized starting from the protected tocopherol chromene 16b which was a key intermediate for preparation of a 3-hydroxy derivative, either by reduction of epoxides produced directly with Jacobsen's catalysts or by treatment with NBS in wet DME to give two stereoisomeric bromohydrins which were cyclized and reduced to give the phenol-protected C-3 alcohols 19a,b. These alcohols were then converted to diazoacetate esters, and the protecting group was removed to give 3-diazoacetoxy α-tocopherols 3a,b.

An easy access to symmetrical Z-olefins from phosphorus ylides

Symmetrical Z-olefins are obtained in good to quantitative yields from phosphonium salts via an autoxidation process, in salt-free conditions.

ω-HYDROXYALKYL-PHOSPHONIUM SALTS AS "INSTANT-YLID" COMPONENTS: EXTREMELY CONVENIENT AND HIGHLY CIS-SELECTIVE SYNTHESIS OF ALKENOL-TYPE PHEROMONES

In less than 2 hours, (Z)-alkenols of 97-98percent stereoisomeric purity may be prepared and isolated (!) if a new type of "instant-ylids" is used.