65738-69-4 Usage
General Description
2-[(adamantan-1-ylmethyl)-amino]-ethanol, also known as memantine, is a medication used to treat Alzheimer's disease. It works by blocking the receptors for a neurotransmitter called glutamate in the brain, which is believed to play a role in the disease's progression. Memantine is derived from the chemical adamantane and has a unique structure that allows it to selectively target certain receptors, helping to reduce the symptoms of Alzheimer's and improve cognitive function. It is generally well-tolerated with minimal side effects, making it a valuable option for the management of this debilitating condition.
Check Digit Verification of cas no
The CAS Registry Mumber 65738-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,7,3 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 65738-69:
(7*6)+(6*5)+(5*7)+(4*3)+(3*8)+(2*6)+(1*9)=164
164 % 10 = 4
So 65738-69-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H23NO/c15-2-1-14-9-13-6-10-3-11(7-13)5-12(4-10)8-13/h10-12,14-15H,1-9H2
65738-69-4Relevant articles and documents
Novel antitumor adamantane-azole gold(I) complexes as potential inhibitors of thioredoxin reductase
Garcia, Adriana,Machado, Rafael Carvalhaes,Grazul, Richard Michael,Lopes, Miriam Teresa Paz,Corrêa, Charlane Cimini,Dos Santos, Hélio F.,De Almeida, Mauro Vieira,Silva, Heveline
, p. 275 - 292 (2016/04/05)
Gold complexes that could act as antitumor agents have attracted great attention. Heterocyclic compounds and their metal complexes display a broad spectrum of pharmacological properties. The present study reports the preparation and characterization of fo
DERIVATIVES OF ADAMANTANE. I. 2-HYDROXYETHYLAMINO DERIVATIVES OF ADAMANTANE
Plakhotnik, V. M.,Kovtun, V. Yu.,Krasutskii, P. A.,Novikova, M. I.,Prokhorov, A. B.,et al.
, p. 1287 - 1290 (2007/10/02)
The reaction of 1-bromoadamantane with hydroxyalkylamines leads to the preferential formation of 1-(aminoalkoxy)adamantanes.The 2-hydroxyethylamino derivatives of the adamantane series were obtained by the reaction of ethylene oxide with the corresponding amines.
