657385-13-2Relevant academic research and scientific papers
The first example of ligand-mediated dehydration of aldoximes
Makarycheva-Mikhailova, Anastassiya V.,Bokach, Nadezhda A.,Haukka, Matti,Kukushkin, Vadim Yu.
, p. 382 - 386 (2003)
The nitrile complex trans-[PtCl4(EtCN)2] reacts with the aldoximes HON=C(H)R [R=C(Ph)(=O), Me, Ph] in CH2Cl2 to afford products of the addition of the aldoxime HON group across the nitrile CN triple bond, i.e. trans-[PtCl4{NH=C(Et)ON=C(H)R}2] (1-3). These compounds were characterized by elemental analyses, FAB MS, IR and 1H and 13C{1H} spectroscopies and X-ray structure determination has been performed for 1. In CHCl3 solution, 1-3 undergo the spontaneous imine ligand splitting to achieve the carboxamide complex trans-[PtCl4{NH=C(Et)OH}2] and RCN thus giving the first example of a ligand-mediated dehydration of aldoximes. The carboxamide and RCN products are also formed upon treatment of trans-[PtCl 4(EtCN)2] with 2 equiv. of HON=C(H)R in CH 2Cl2.
