657395-91-0Relevant academic research and scientific papers
Exo Selective Enantioselective Nitrone Cycloadditions
Sibi, Mukund P.,Ma, Zhihua,Jasperse, Craig P.
, p. 718 - 719 (2007/10/03)
We have developed a novel method for accessing exo adducts with high enantioselectivity in nitrone cycloadditions to enoates. Pyrazolidinones proved to be effective achiral templates in the cycloadditions, providing exo adducts typically in >15:1 selectivity and 90-98% ee. The use of Lewis acids that form square planar complexes, such as copper triflate, was important for obtaining high exo selectivity. Copyright
