65755-81-9Relevant academic research and scientific papers
Facile access to 2,2-disubstituted indolin-3-ones: Via a cascade Fischer indolization/Claisen rearrangement reaction
Xia, Zilei,Hu, Jiadong,Gao, Yu-Qi,Yao, Qizheng,Xie, Weiqing
supporting information, p. 7485 - 7488 (2017/07/12)
An efficient approach for the synthesis of 2,2-disubstituted indolin-3-ones is described. From readily accessible aryl hydrazines and allyloxyketones, 2,2-disubstituted indolin-3-ones could be obtained in good to excellent yields under mild reaction condi
Catalytic ketyl-olefin cyclizations enabled by proton-coupled electron transfer
Tarantino, Kyle T.,Liu, Peng,Knowles, Robert R.
supporting information, p. 10022 - 10025 (2013/07/26)
Concerted proton-coupled electron transfer is a key mechanism of substrate activation in biological redox catalysis. However, its applications in organic synthesis remain largely unexplored. Herein, we report the development of a new catalytic protocol fo
Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator
Nique, Francois,Hebbe, Severine,Triballeau, Nicolas,Peixoto, Christophe,Lefrancois, Jean-Michel,Jary, Helene,Alvey, Luke,Manioc, Murielle,Housseman, Christopher,Klaassen, Hugo,Van Beeck, Kris,Guedin, Denis,Namour, Florence,Minet, Dominque,Van Der Aar, Ellen,Feyen, Jean,Fletcher, Stephen,Blanque, Roland,Robin-Jagerschmidt, Catherine,Deprez, Pierre
supporting information, p. 8236 - 8247,12 (2020/09/15)
Structural modification performed on a 4-methyl-4-(4-hydroxyphenyl) hydantoin series is described which resulted in the development of a new series of 4-(hydroxymethyl)diarylhydantoin analogues as potent, partial agonists of the human androgen receptor. T
NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS
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Page/Page column 41, (2010/04/06)
Novel compounds are disclosed that have a Formula represented by the following: wherein X, R1, R2a, R2b, R2c, R3a R3b, R4a, R4b, R4c, and ml are as describe
An alternative to the Swern oxidation
Bisai, Alakesh,Chandrasekhar,Singh, Vinod K.
, p. 8355 - 8357 (2007/10/03)
A variety of alcohols have been oxidized under mild conditions by the DMSO-Ph3P·X2 complexes. The reaction does not produce any Pummerer product. A mechanism for the reaction is proposed.
