65786-23-4Relevant academic research and scientific papers
Skin Whitening Composition comprising Chalcone Derivatives
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Paragraph 0167-0172, (2020/03/03)
The present invention relates to a skin whitening composition comprising a chalcone derivative. The composition can effectively suppress the production of melanin, and thus can be advantageously used for whitening of the skin in which melanin is excessive
Evaluation and optimization of the antimelanogenic activity of 1-(2-cyclohexylmethoxy-6-hydroxy-phenyl)-3-(4-hydroxymethyl-phenyl)-propenone derivatives
Kim, Byung-Hak,Hong, Soo-Nam,Ye, Sang-Kyu,Park, Jung-Youl
, (2019/04/17)
The chemical modification and optimization of biologically active compounds are essential steps in the identification of promising lead compounds for drug development. We previously reported the anti-melanogenic activity of 1-(2-cyclohexylmethoxy-6-hydrox
Structural requirement of chalcones for the inhibitory activity of interleukin-5
Yang, Hyun-Mo,Shin, Hye-Rim,Cho, Soo-Hyun,Bang, Seong-Cheol,Song, Gyu-Yong,Ju, Jung-Hun,Kim, Mi-Kyeong,Lee, Seung-Ho,Ryu, Jae-Chun,Kim, Youngsoo,Jung, Sang-Hun
, p. 104 - 111 (2007/10/03)
Novel chalcones were found as potent inhibitors of interleukin (IL)-5. 1-(2-Benzyloxy-6-hydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one (2b, 78.8% inhibition at 50 μM, IC50 = 25.3 μM) was initially identified as a potent inhibitor of IL-5. Th
