6579-47-1Relevant academic research and scientific papers
Site-selective conversion of azido groups at carbonyl α-positions into oxime groups leading triazide to a triple click conjugation scaffold
Yokoi, Taiki,Ueda, Tomomi,Tanimoto, Hiroki,Morimoto, Tsumoru,Kakiuchi, Kiyomi
, p. 1891 - 1894 (2019)
This paper reports the selective conversion of alkyl azido groups at the carbonyl α-position into oximes through β-elimination of dinitrogen, followed by transoximation. With this method and diazo conversion, a triazido molecule was transformed into a triple click conjugation scaffold allowing one-pot four-component coupling.
