6579-55-1

Usage

Uses

Used in Pharmaceutical Industry:
1-[(2-hydroxyethyl)amino]propan-2-ol is used as a solvent and stabilizer for its ability to dissolve a wide range of substances and maintain the stability of pharmaceutical formulations. Its mild properties make it suitable for use in medications and other healthcare products.
Used in Personal Care Industry:
In personal care products, 1-[(2-hydroxyethyl)amino]propan-2-ol is utilized as a solvent and stabilizer, contributing to the consistency, texture, and longevity of products such as creams, lotions, and shampoos.
Used in Plastics and Resins Production:
1-[(2-hydroxyethyl)amino]propan-2-ol is employed in the production of plastics and resins due to its compatibility with various polymers and its ability to improve the properties of the final products, such as flexibility and durability.
Used in Dyes Production:
1-[(2-hydroxyethyl)amino]propan-2-ol is also used in the production of dyes, where it can enhance the solubility and color intensity of dye molecules, making them more effective in coloring fabrics and other materials.

InChI:InChI=1/C5H13NO2/c1-5(8)4-6-2-3-7/h5-8H,2-4H2,1H3

Upstream product

• 141-43-5 ethanolamine 
• 75-56-9 methyloxirane 
• 106345-18-0 1-(2-Methyl-1-oxa-4-aza-spiro[4.5]dec-4-yl)-propan-2-ol 
• 78-96-6 3-amino-2-propanol 
• 107-07-3 2-chloro-ethanol 
• 20958-86-5 2-acetoxy-1-(2-isopropyl-oxazolidin-3-yl)-propane 

Downstream Products

• 109-00-2 3-HYDROXYPYRIDINE 
• 93309-84-3 N-(2-Hydroxy-propyl)-N-(2-hydroxy-aethyl)-1-amino-2-hydroxy-2-phenyl-aethan 
• 26562-68-5 2,6a-dimethyl-tetrahydro-oxazolo[2,3-b]oxazole 
• 51477-02-2 3-Methyl-5-ethyl-4,6-dioxa-1-aza-bicyclo<3.3.0>octan 
• 16562-68-8 N-(2-Hydroxy-ethyl)-N-(2-hydroxy-propyl)-3,4,5-trimethoxy-zimtsaeure-amid 
• 10353-86-3 N,N-bis(2-hydroxypropyl)-N-(hydroxyethyl)amine 
• 27550-90-9 2-methylmorpholine 
• 25772-54-7 Benzyl-(2-chloro-ethyl)-(2-chloro-propyl)-amine 
• 25772-53-6 1-[(2-hydroxyethyl)(phenylmethyl)amino]-2-propanol 

Relevant academic research and scientific papers

Prediction of structures, properties, and functions of alternating copolymers of ethylene imine and ethylene oxide as an example of molecular design for polymers

Conformational analysis of two alternating copolymers, poly(ethylene imine-alt-ethylene oxide) (PEIEO) and poly(N-methylethylene imine-alt-ethylene oxide) (PMEIEO), has been carried out by the inversional-rotational isomeric state (IRIS) analysis of ab initio molecular orbital (MO) calculations and 1H and 13C NMR experiments for their model compounds. On the basis of the conformational energies derived therefrom and molecular mechanics and MO calculations, higher-order structures, physical properties, and functions of the two copolymers have been predicted as an example of molecular design. These copolymers are expected to form various hydrogen bonds: PEIEO, N-H...O (interaction energy, -1.75 kcal mol-1), C-H...N (-0.68 kcal mol-1), and C-H...O (-0.21 kcal mol-1); PMEIEO, C-H...N (-0.66 kcal mol-1), and C-H...O (-0.41 kcal mol-1). In particular, the N-H...O hydrogen bond of PEIEO is too strong to be broken even by protic solvents such as methanol and water but replaced by an intermolecular N-H...O=S attraction in dimethyl sulfoxide. The C-N and C-O bonds of PEIEO prefer the trans state as found for poly(ethylene imine) (PEI) and poly(ethylene oxide), whereas the C-C bond does not have its own conformational preference and its conformational equilibrium is determined only by the hydrogen bond strength (HBS). The characteristic ratio of PEIEO largely depends on HBS: 1.5 (HBS = 100%); 6.5 (0%). In contrast, the weak hydrogen bonds of PMEIEO little affect the characteristic ratio; 5.2 (HBS = 100%); 5.9 (0%). According to Mattice's analysis (Macromolecules 2004, 37, 4711), PEIEO and PEI tend to form circular paths due to the intramolecular hydrogen bonds. Both molecular mechanics calculations using the Amber force field and density functional MO calculations under the periodic boundary condition have suggested that a double-helical structure may be formed in the PEIEO crystal. The possibility that these copolymers will be utilized as gene carriers and ion conductors is discussed, and the synthetic method is also suggested. In conclusion, these copolymers should be promising and deserve to be synthesized.

OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES

It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.

Synthesis of Monoaza Crown Ethers from N,N-Diamines and Oligoethylene Glycol Di(p-toluenesulfonates) or Corresponding Dichlorides

Monoaza crown ethers were prepared in satisfactory yields by the one-step reaction between diethanolamine or N,N-diamines and oligoethylene glycol di(p-toluenesulfonates) or corresponding dichlorides in t-butyl alcohol/dioxane in the presence of sodium or potassium t-butoxide.The reaction conditions in the preparation of monoaza 15- and 18-crown ethers were studied.Various monoaza crown ethers having substituents were also prepared and their properties were investigated.