658041-41-9Relevant academic research and scientific papers
Synthesis and study of some properties of 1-aryl-2-oxo-1,2,3,6- tetrahydro[1,4]diazepino[6,5-b]indole 4-oxides
Ryabova,Rastorgueva,Lisitsa,Alekseeva,Granik
, p. 1386 - 1398 (2007/10/03)
A number of 1-aryl-2-oxo-1,2,3,6-tetrahydro[1,4]diazepirio[6,5-b]indole 4-oxides were synthesized based on 3-[N-aryl-N-(chloroacetyl)amino]-2- formylindoles. The nature of the substituent in the 1-aryl fragment has a pronounced influence on the course of reactions throughout the whole sequence of transformations during the synthesis of diazepinoindoles. The reduction of 4-oxides by formamidinosulfinic acid, hydrogen in the presence of Pd/C, and sodium bisulfite was studied. The structures of the reaction products were confirmed using IR and 1H NMR spectroscopy and mass spectrometry.
