658052-77-8

Upstream product

• 114185-07-8 ethyl (2R)-2-[(1S)-3,3-dimethyl(2,4-dioxolanyl)]-2-hydroxyacetate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1202878-68-9 ethyl 2-(O-tert-butyldiphenylsilyl)-L-threonate 
• 658052-82-5 (4S,5S)-5-[(R)-(tert-Butyl-diphenyl-silanyloxy)-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid ethyl ester 
• 658052-81-4 (2S,3S,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydroxy-butyric acid ethyl ester 
• 658052-88-1 (4R,5S)-5-[(R)-(tert-Butyl-diphenyl-silanyloxy)-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid methyl ester 
• 658052-87-0 (2R,3S,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydroxy-butyric acid methyl ester 
• 658052-83-6 (4S,5S)-5-[(R)-(tert-Butyl-diphenyl-silanyloxy)-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 658052-89-2 (4R,5S)-5-[(R)-(tert-Butyl-diphenyl-silanyloxy)-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 658052-80-3 (E)-(S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-but-2-enoic acid ethyl ester 
• 658052-86-9 (Z)-(S)-4-(tert-Butyl-diphenyl-silanyloxy)-4-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-but-2-enoic acid methyl ester 
• 732276-05-0 (2R,5R,6S)-3-benzenesulfonyl-1-benzyloxy-5-tert-butyldiphenylsilyloxy-2-tert-butoxycarbonylamino-4-hydroxy-6,7-O-isopropylidene-6,7-dihydroxyheptane 
• 658052-79-0 (2R,3S)-2-O-tert-butyldiphenylsilyloxy-3,4-O-isopropylidene-3,4-dihydroxybutanal 
• 658052-78-9 (2S,3S)-2-O-tert-butyldiphenylsilyloxy-3,4-O-isopropylidene-3,4-dihydroxybutanol 

Relevant academic research and scientific papers

Versatile approach to enantiopure 2,6-disubstituted piperidin-3-ol framework: Application to the total synthesis of (+)-deoxoprosopinine

An efficient synthesis of enantiopure 2,6-disubstituted piperidin-3-ol 19 is developed featuring two key steps: (a) Julia olefination of (2R)-3-phenylsulfonyl-2-tert-butyloxycarbamoylpropanol benzyl ether 9B and (2R,3S)-2-tert-butyldiphenyl-3,4-O-isopropy

Synthetic studies towards diazepanone scaffolds

The synthesis of new enantiopure polyfunctionalised diazepanone scaffolds is described. The key steps involve the opening of an azido-epoxide C4 building block derived from l-ascorbic or d-isoascorbic acid by a l-serine derivative followed by a lactonisation-lactamisation two-step sequence.

Novel Route to L-Hexoses from L-Ascorbic Acid: Asymmetric Synthesis of L-Galactopyranose and L-Talopyranose. Preliminary Communication

A novel route with L-ascorbic acid as a single common starting material to asymmetric synthesis of all eight diastereomers of L-hexoses is described. Assessment of this new approach is demonstrated by the expedient synthesis of L-galactopyranose and L-tal