65806-45-3Relevant academic research and scientific papers
Analgesic and/or opiate antagonist tripeptide amides and processes for preparation and compositions thereof
-
, (2008/06/13)
A genus of tripeptide amides and fifteen species thereof of Examples 4-18, which are useful as analgesics and/or opiate antagonists, three processes for preparation thereof, pharmaceutical compositions thereof, and the three tripeptide amide species of Examples 1-3, which are not within the genus and are useful as analgesics and/or opiate antagonists, are disclosed.
Analgesic dipeptide amides and method of use and composition thereof
-
, (2008/06/13)
A genus of dipeptide amides including as the preferred subgenus the dipeptide amides having the structural formula HTyrD-AlaNR2 R3 wherein R2 is phenylalkyl or substituted-phenylalkyl and R3 is hydrogen, alkyl, phenylalkyl, substituted-phenylalkyl or X-alkyl wherein X is an electronegative moiety are prepared by condensing the dipeptide with the amine or the amino acid with the amino acid amide and are useful as analgesics.
