65806-90-8

Usage

Uses

Used in Pharmaceutical Development:
Z-D-SER(TBU)-OH is used as a building block for the development of new pharmaceuticals, contributing to the creation of innovative drugs with potential therapeutic applications.
Used in Peptide Synthesis:
In the field of organic chemistry, Z-D-SER(TBU)-OH is utilized as a precursor in the synthesis of various peptides, playing a crucial role in the assembly of complex peptide structures.
Used in Research Laboratories:
Z-D-SER(TBU)-OH is employed in research settings for the study of biochemical pathways and protein interactions, aiding scientists in understanding fundamental biological processes and mechanisms.
Used in Organic Synthesis:
As a protecting group, Z-D-SER(TBU)-OH is used in organic synthesis to prevent unwanted reactions, ensuring the selective formation of desired compounds and facilitating the synthesis of complex organic molecules.

Upstream product

• 93204-37-6 (2R)-2-(benzyloxycarbonylamino)-3-tert-butoxypropionic acid methyl ester 
• 1872-59-9 (S)-methyl 2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoate 

Downstream Products

• 78700-43-3 Z-D-Ser(Bu^t)-OTce 
• 935878-62-9 C₁₈H₂₇NO₅ 
• 1333115-00-6 (S)-2-((2-amino-3-(tert-butoxy)propoxy)methyl)benzoic acid 
• 1333115-01-7 C₁₆H₂₅NO₄ 
• 1333114-99-0 (S)-methyl 2-((2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propoxy)methyl)benzoate 
• 1333114-97-8 (S)-benzyl (1-(tert-butoxy)-3-hydroxypropan-2-yl)carbamate 
• 1084734-33-7 (R)-2-acetamido-N-benzyl-3-tert-butoxypropionamide 
• 1282623-42-0 O-tert-butyl-D-serine benzylamide 
• 1282623-41-9 O-tert-butyl-N-Z-D-serine benzylamide 
• 713122-17-9 (Z)-D-Ser{Fmoc-D-Ser[Boc-L-Ala-L-Cys(Acm)-L-Val]-L-Ala-L-Cys(Acm)-L-Val}-OTce 
• 713122-18-0 (Z)-D-Ser{Fmoc-D-Ser[Boc-L-Ala-L-Cys(Acm)-L-Val]-L-Ala-L-Cys(Acm)-L-Val}-OH 
• 713122-19-1 C₅₆H₇₂N₈O₁₇S₂ 
• 713122-20-4 [(1R,4S,7R,11S,14R,17S,20R,24S)-20-(9H-Fluoren-9-ylmethoxycarbonylamino)-11,24-diisopropyl-4,17-dimethyl-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexaaza-bicyclo[12.12.4]triacont-7-yl]-carbamic acid benzyl ester 
• 713122-03-3 (Z)-D-Ser[N-Boc-L-Ala-L-Cys(Acm)-L-Val]-OTce 

Relevant academic research and scientific papers

Synthesis of 6, desGly10>GnRH-Et without Side-Chain Protection

A gonadoliberin superagonist, 6, desGly1>GnRH-Et* (5), was obtained in solution by connecting segments, Glp-His-Trp-Ser-Tyr-N2H3 (1) and Z-DSer(tBu)-LeuArg(AcOH)-Pro-NHEt (4) (Scheme 1), which were produced witho

Biosynthesis of Hyalodendrin and Didethiobis(methylthio)hyalodendrin, Sulphur-containing 2,5-Dioxopiperazines of the 3S,6S Series

cyclo-(L-Phe-L-Ser) 8, a known biosynthetic precursor of the (3R,6R)-epidithiodioxopiperazine gliotoxin 4, was efficiently incorporated (42percent), in Hyalodendron sp. (FSC-601) cultures, into the 3S,6S metabolite didethiobis(methylthio)hyalodendrin (DBH) 7 without significant change in the 3H:14C ratio.None of the three diasteromers of cyclo-(L-Phe-L-Ser) was incorporated into DBH to any significant extent.The 13C label from cyclo-(L-Phe-L-Ser) was located, in the expected site, in DBH by 13C NMR spectroscopy.Gliotoxin derived in Gliocladium virens from the doubly labelled precursor 8 was degraded to locate, in similar manner, the 14C label.The N-methyl derivative 16 of cyclo-(L-Phe-L-Ser) was not incorporated detectably into either gliotoxin or DBH.Radioactivity from the doubly labelled, linear dipeptides 17 and 18, possible precursors for the cyclodipeptide 8, was incorporated with moderate efficiency into gliotoxin.However, the 3H:14C ratios for the dipeptides and the derived gliotoxin differd substantially, indicating that the peptides had undergone cleavage in the fungus before incorporation.