658061-59-7Relevant articles and documents
Structure and activity relationships of novel uracil derivatives as topical anti-inflammatory agents
Isobe, Yoshiaki,Tobe, Masanori,Inoue, Yoshifumi,Isobe, Masakazu,Tsuchiya, Masami,Hayashi, Hideya
, p. 4933 - 4940 (2007/10/03)
In order to create novel, topical anti-inflammatory compounds exhibiting more potent activities than lead compound CX-659S (1), we designed and synthesized various derivatives of 1 focusing on the uracil N(1)- and N(3)-substituents, and evaluated their an