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658080-72-9

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658080-72-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 658080-72-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,8,0,8 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 658080-72:
(8*6)+(7*5)+(6*8)+(5*0)+(4*8)+(3*0)+(2*7)+(1*2)=179
179 % 10 = 9
So 658080-72-9 is a valid CAS Registry Number.

658080-72-9Upstream product

658080-72-9Downstream Products

658080-72-9Relevant academic research and scientific papers

A PROCESS FOR THE PREPARATION OF ESCITALOPRAM

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Page/Page column 12, (2010/10/20)

The present invention relates to an improved process for the preparation of escitalopram of the formula-(I) which consists of a sequential double Grignard reaction on 5-iodophthalide to get the dihydroxy compound of formula-(XVI), its resolution using a chiral acid, cyclization of resolved compound of the formula-(XVII), and cyanation of compound of the formula-(XVIII) using DMF and copper (I) cyanide. The present process utilizes the facile displacement of iodo group with cyano group in the final step of escitalopram. Escitalopram is a widely used anti-depressant.

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