6582-06-5

Usage

Uses

Used in Pharmaceutical Research and Development:
(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)prop-2-enenitrile is used as a chemical compound in the research and development of pharmaceuticals and organic synthesis. Its unique chemical properties and potential biological activities make it a promising candidate for the development of new drugs for various diseases and medical conditions.
Used in Anti-inflammatory Applications:
(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)prop-2-enenitrile is used as an anti-inflammatory agent. Its potential anti-inflammatory properties make it a candidate for the development of new treatments for inflammatory diseases and conditions.
Used in Anti-cancer Applications:
(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)prop-2-enenitrile is used as an anti-cancer agent. Its potential anti-cancer properties make it a candidate for the development of new treatments for various types of cancer.
Used in Drug Development:
(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)prop-2-enenitrile is used in the development of new drugs for various diseases and medical conditions. Its unique chemical properties and potential biological activities make it a promising candidate for the development of innovative therapeutic agents.

Upstream product

• 104-47-2 p-methoxybenzylnitrile 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 1222-61-3 (Z)-3-(4-(dimethylamino)phenyl)-2-phenylacrylonitrile 

Downstream Products

• 108472-63-5 Trifluoro-methanesulfonate{4-[(Z)-2-cyano-2-(4-methoxy-phenyl)-vinyl]-phenyl}-trimethyl-ammonium; 
• 72035-49-5 3-(4-Dimethylamino-phenyl)-2-(4-methoxy-phenyl)-propionitrile 

Relevant academic research and scientific papers

Accelerated Discovery of α-Cyanodiarylethene Photoswitches

Cyanodiarylethene chromophores are able to undergo constitutional exchange via dynamic covalent chemistry (DCC). During this process, the central ethylene bridge of the molecular scaffold can be broken and thereby enables the assembly of a new combination of aryl moieties around the reformed ethylene bridge. The reversible CC double bond exchange has exemplarily been investigated using α-cyanostilbenes. Establishing a dynamic equilibrium reaction from α-cyanodiarylethene with arylacetonitriles under mild conditions has been the basis to access constitutional libraries of new photoswitches with potentially improved properties. When subject to irradiation with light of adequate wavelength, α-cyanodiarylethenes undergo Z/E isomerization followed by ring-closure. By screening the thus accessible dynamic chromophore libraries using a desired detection wavelength, we could identify specific dithienyl analogues that exhibit three-state photochromism. The combination of dynamic constitutional libraries of functional chromophores in combination with the light-guided screening and selection should lead to more rapid exploration of structural diversity dye chemistry.

Substituent effect on the solid-state photoinduced luminescence of α-cyanostilbene derivatives

Summary: A series of α-cyanostilbene derivatives with aggregation-induced enhanced emission （ AIEE ） was obtained. All the compounds were characterized by UV?vis spectroscopy, fluorescence and nuclear magnetic resonance. These compounds exhibited blue, gr

(Z)-2-(2-bromophenyl)-3-{[4-(1-methyl-piperazine)amino]phenyl}acrylonitrile (DG172): An orally bioavailable PPARβ/δ-selective ligand with inverse agonistic properties

The ligand-regulated nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a potential pharmacological target due to its role in disease-related biological processes. We used TR-FRET-based competitive ligand binding and coregulator

Synthesis and Properties of Quaternary Ammonium Salts of Substituted α-Phenylcinnamonitriles

Quaternary ammonium salts of substituted α-phenylcinnamonitriles were synthesized via base-catalyzed condensations of substituted phenylacetonitriles and aldehydes, followed by alkylation of the amino moieties with dimethyl sulfate or methyl trifluorometh