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NHS-PEO2-NHS(BS[PEG]2) is a PEG-based molecule with two NHS ester groups and a bis-sulfone (BS) linker. The hydrophilic PEG spacer enhances solubility in aqueous media, while the NHS esters can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

65869-63-8

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65869-63-8 Usage

Uses

Used in Bioconjugation:
NHS-PEO2-NHS(BS[PEG]2) is used as a crosslinking agent for the formation of stable amide bonds between primary amines of proteins, peptides, and other amine-containing molecules. The bis-sulfone linker provides enhanced stability and reduced hydrolysis compared to traditional homobifunctional crosslinkers.
Used in Drug Delivery Systems:
In the pharmaceutical industry, NHS-PEO2-NHS(BS[PEG]2) is used as a component in the development of drug delivery systems. The PEG spacer and NHS esters can be utilized to attach drug molecules to targeting ligands or other therapeutic agents, improving the solubility, stability, and bioavailability of the drug.
Used in Diagnostic Imaging:
In the medical imaging field, NHS-PEO2-NHS(BS[PEG]2) can be used as a bifunctional chelator for the conjugation of imaging agents, such as radionuclides or fluorescent dyes, to targeting molecules. This allows for the development of targeted imaging probes with improved sensitivity and specificity.
Used in Biosensor Development:
In the biosensor industry, NHS-PEO2-NHS(BS[PEG]2) is used as a key component in the fabrication of biosensors. The PEG spacer and NHS esters can be employed to immobilize recognition elements, such as enzymes, antibodies, or oligonucleotides, onto sensor surfaces, enhancing the stability and performance of the biosensors.

Check Digit Verification of cas no

The CAS Registry Mumber 65869-63-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,8,6 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65869-63:
(7*6)+(6*5)+(5*8)+(4*6)+(3*9)+(2*6)+(1*3)=178
178 % 10 = 8
So 65869-63-8 is a valid CAS Registry Number.

65869-63-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,1'-{1,2-Ethanediylbis[oxy(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyr rolidinedione)

1.2 Other means of identification

Product number -
Other names NHS-PEO2-NHS(BS[PEG]2)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65869-63-8 SDS

65869-63-8Upstream product

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