658858-65-2 Usage
Description
THP-PEG10 is a PEGylated compound consisting of a polyethylene glycol (PEG) linker with a molecular weight of approximately 10 kDa and a trityl (THP) protecting group. The THP group serves as an alcohol protecting group that can be removed under acidic conditions, while the hydrophilic PEG linker enhances the water solubility of the compound in aqueous media. This unique structure makes THP-PEG10 a versatile molecule with potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
THP-PEG10 is used as a drug delivery carrier for improving the solubility, stability, and bioavailability of therapeutic molecules. The PEG linker provides increased water solubility, while the THP group can be removed under specific conditions to release the active pharmaceutical ingredient.
Used in Bioconjugation:
THP-PEG10 is used as a bioconjugation agent for the site-specific attachment of biologically active molecules, such as peptides, proteins, or nucleic acids, to other molecules or surfaces. The THP group can be selectively removed under acidic conditions, allowing for the controlled release of the conjugated molecule.
Used in Diagnostics:
THP-PEG10 can be employed as a contrast agent in medical imaging techniques, such as magnetic resonance imaging (MRI) or computed tomography (CT), due to its ability to alter the properties of the surrounding environment and enhance image contrast.
Used in Cosmetics Industry:
THP-PEG10 is used as a solubility enhancer and stabilizing agent in the formulation of cosmetics and personal care products. The hydrophilic PEG linker improves the solubility of various ingredients, while the THP group provides protection and controlled release properties.
Used in Material Science:
THP-PEG10 can be utilized in the development of hydrogels, coatings, and other materials with tailored properties. The PEG linker contributes to the hydrophilicity and water retention capacity, while the THP group allows for controlled release of embedded molecules or stimuli-responsive behavior.
Check Digit Verification of cas no
The CAS Registry Mumber 658858-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,8,8,5 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 658858-65:
(8*6)+(7*5)+(6*8)+(5*8)+(4*5)+(3*8)+(2*6)+(1*5)=232
232 % 10 = 2
So 658858-65-2 is a valid CAS Registry Number.
658858-65-2Relevant articles and documents
Water soluble homogeneous catalysts that are recoverable by phase selectivity and host-guest interactions
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Page/Page column 6, (2020/08/30)
A chemical reaction is catalyzed in an organic solvent using a water soluble N-heterocyclic carbene homogeneous catalyst to form a reaction mixture. An aqueous phase in the reaction mixture. A solvent in which the catalyst is insoluble is added to the reaction mixture, causing the catalyst to migrate to the aqueous phase to form a catalyst-laden aqueous phase. The catalyst is extracted from the catalyst-laden aqueous phase.
Synthesis and Molecular Recognition of Pyrenophanes with Polycationic or Amphiphilic Functionalities: Artificial Plate-Shaped Cavitant Incorporating Arenes and Nucleotides in Water
Abe, Hajime,Mawatari, Yosuke,Teraoka, Haruna,Fujimoto, Kazuhisa,Inouye, Masahiko
, p. 495 - 504 (2007/10/03)
Water-soluble pyrenophanes possessing polycationic or amphiphilic side chains have been developed as synthetic host molecules to investigate hydrophobic and/or π-stacking interactions. By utilizing ω-acetalic alkyl side chains to retain solubility and ver
