65894-01-1Relevant academic research and scientific papers
Substituted benzopyranones as telomerase inhibitors
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, (2008/06/13)
The present invention relates to benzopyranone derivatives, to methods for treating telomerase-modulated diseases, in particular cancers, with said derivatives, to a process for their preparation, to their use as medicaments and to pharmaceutical compositions comprising them.
SYNTHESE DE TRIHYDROXYPHENACYLIDENETRIPHENYLPHOSPHORANES UNE NOUVELLE VOIE D'ACCES AUX DIHYDROXYFLAVONES (CHRYSINE, ACACETINE...)
Le Floc'H, Yves,Lefeuvre, Martine
, p. 5503 - 5504 (2007/10/02)
An easy and convenient synthesys of two new trihydroxyphenacylidenetriphenylphosphoranes from phloroglucinol and pyrogallol is described.Some dihydroxyflavones are prepared by acylation of these ylids, intramolecular olefination and saponification of the two remaining ester groups.
