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2,2,2-Trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide is a chemical compound characterized by its molecular formula C6H4F3N3O3S. It is a trifluoromethylated derivative of the antibiotic nitrofurazone, featuring a thiazole ring with a nitro group attached. 2,2,2-trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide is recognized for its antibacterial and antifungal properties, making it a significant player in the pharmaceutical industry. Its role as a pharmaceutical intermediate and its trifluoromethyl group contribute to its value in medicinal chemistry research and drug development, as well as in the synthesis of fluorinated pharmaceuticals.

659-13-2

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659-13-2 Usage

Uses

Used in Pharmaceutical Industry:
2,2,2-Trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide is used as a pharmaceutical intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and properties. Its presence as a trifluoromethylated derivative enhances the bioactivity and pharmacokinetic profile of the resulting drugs.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2,2,2-trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide is utilized as a key compound for research and development. Its structural features allow for the exploration of new drug candidates with improved therapeutic potential.
Used in Drug Development:
2,2,2-trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide serves as a valuable building block in drug development, particularly for the production of fluorinated pharmaceuticals. The trifluoromethyl group is known to impart specific properties to drugs, such as increased metabolic stability and lipophilicity, which can lead to enhanced drug efficacy and bioavailability.
Used in Antibacterial and Antifungal Agents:
2,2,2-Trifluoro-N-(5-nitro-1,3-thiazol-2-yl)acetamide is employed as an active ingredient in the development of antibacterial and antifungal agents, leveraging its inherent antimicrobial properties to combat a range of infections.

Check Digit Verification of cas no

The CAS Registry Mumber 659-13-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 659-13:
(5*6)+(4*5)+(3*9)+(2*1)+(1*3)=82
82 % 10 = 2
So 659-13-2 is a valid CAS Registry Number.

659-13-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,2-trifluoro-N-(5-nitrothiazol-2-yl)acetamide

1.2 Other means of identification

Product number -
Other names 2-Trifluor-1-<trifluormethyl-hydroxy-methoxy>-ethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:659-13-2 SDS

659-13-2Downstream Products

659-13-2Relevant academic research and scientific papers

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