6590-97-2

Usage

Uses

Used in Agrochemical Industry:
2,3-Dichlorophenyl isothiocyanate serves as an intermediate in the synthesis of various agrochemicals, contributing to the development of effective pest control agents and other agricultural products. Its reactivity allows for the creation of compounds with specific pesticidal properties, enhancing crop protection and yield.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,3-Dichlorophenyl isothiocyanate is utilized as an intermediate for the synthesis of a range of pharmaceuticals. Its unique chemical structure enables the production of compounds with targeted therapeutic effects, contributing to the advancement of medicinal chemistry and drug development.
Used in Organic Synthesis:
2,3-Dichlorophenyl isothiocyanate is employed as a versatile intermediate in organic synthesis, facilitating the creation of a variety of organic compounds with diverse applications. Its reactivity and functional group make it a valuable component in the synthesis of specialty chemicals, dyes, and other industrial products.

InChI:InChI=1/C7H3Cl2NS/c8-5-2-1-3-6(7(5)9)10-4-11/h1-3H

Upstream product

• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 135085-67-5 Indole-1-carbothioic acid (2,3-dichloro-phenyl)-amide 
• 140136-63-6 2-(2,3-dichlorophenylamino)-4H-3,1-benzothiazin-4-one 
• 75257-58-8 1-(2-Amino-ethyl)-3-(2,3-dichloro-phenyl)-thiourea 
• 75564-79-3 1-cyano-3-(2,3-dichlorophenyl)-2-methylisothiourea 
• 139059-02-2 1-(2,3-dichloro-phenyl)-1H-tetrazole-5-thiol 
• 861259-01-0 2-(2,3-dichloro-phenylamino)-4-methoxy-3H-benzoimidazole-5-carboxylic acid methyl ester 
• 861258-99-3 2-(2,3-dichloro-phenyl-amino)-7-methoxy-1H-benzoimidazole-5-carbonitrile 
• 861259-02-1 6-bromo-2-(2,3-dichloro-phenylamino)-3H-benzoimidazole-4-carboxylic acid methyl ester 
• 182572-36-7 N-(2,3-dichloro)phenyl-N'-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiourea 
• 186543-23-7 N-(2,3-dichloro)phenyl-N'-(3-(dimethyl)amino-1,2,3,4-tetrahydro-9H-carbazol-6-yl)thiourea 

Relevant academic research and scientific papers

COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION

Heterocyclic compounds with a novel pyrazole thioamide-based NNSN structural motif, having highly effective zinc- or copper-activated toxicity against microbial infections at micromolar or nanomolar minimum inhibitory concentrations (MIC), and methods of making and using same.

N,N'-bis-substituted aryl thiourea derivatives and synthetic method and application thereof

The invention discloses N,N'-bis-substituted aryl thiourea derivatives which are a series of compounds simultaneously containing various substituted aromatic ring structures and asymmetric substituted thiourea structures and are all novel structural compounds which are not reported in the literature. The biological activity test analysis of all the target compounds includes determination of DPPH antioxidant activity and antiviral activity. Results indicate that, in general, the designed and synthesized compounds are novel in structures and have the antioxidant activity and the antiviral activity revealed for the first time. In addition, the unknown biological activity is not fully elucidated, and thus the compounds are expected to provide a certain material basis for further research and development of new drugs.

Facile and versatile synthesis of alkyl and aryl isothiocyanates by using triphosgene and cosolvent

A mild and efficient method for the conversion of alkyl and aryl amines to isothiocyanates via dithiocarbamates has been developed using (CH 3)2CO-CS2 as co-solvent and triphosgene as dehydrosulfurization reagent. High yields, mild reaction conditions and excellent functional group compatibility make it become a versatile synthetic method for the preparation of isothiocyanates compared with reported methods. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]