6590-97-2

Basic information

• Product Name: 2,3-DICHLOROPHENYL ISOTHIOCYANATE
• Synonyms: 2,3-DICHLOROPHENYL ISOTHIOCYANATE;2,3-Dichlorophenyl isothiocyate, 98%
• CAS NO: 6590-97-2
• Molecular Formula: C₇H₃Cl₂NS
• Molecular Weight: 204.08
• EINECS: -0
• Product Categories: Organic Building Blocks;Sulfur Compounds;Thiocyanates/Isothiocyanates;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfur Compounds
• Mol File: 6590-97-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 257°C
• Boiling Point: 256-258 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.434 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00104mmHg at 25°C
• Refractive Index: n20/D 1.675(lit.)
• Sensitive: Moisture Sensitive
• BRN: 2091585
• CAS DataBase Reference: 2,3-DICHLOROPHENYL ISOTHIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLOROPHENYL ISOTHIOCYANATE(6590-97-2)
• EPA Substance Registry System: 2,3-DICHLOROPHENYL ISOTHIOCYANATE(6590-97-2)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 6590-97-2(Hazardous Substances Data)

Usage

General Description

2,3-Dichlorophenyl isothiocyanate is a chemical compound that contains two chlorine atoms and an isothiocyanate functional group. It is commonly used as an intermediate in the synthesis of various organic compounds, particularly in the production of agrochemicals and pharmaceuticals. 2,3-DICHLOROPHENYL ISOTHIOCYANATE is known for its strong and pungent odor and is considered to be a reactive and toxic substance. It is important to handle 2,3-Dichlorophenyl isothiocyanate with caution and follow appropriate safety measures when working with it in a laboratory or industrial setting.

InChI:InChI=1/C7H3Cl2NS/c8-5-2-1-3-6(7(5)9)10-4-11/h1-3H

Upstream product

• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 75257-58-8 1-(2-Amino-ethyl)-3-(2,3-dichloro-phenyl)-thiourea 
• 75564-79-3 1-cyano-3-(2,3-dichlorophenyl)-2-methylisothiourea 
• 139059-02-2 1-(2,3-dichloro-phenyl)-1H-tetrazole-5-thiol 
• 285125-00-0 (4S)-2-(2,3-dichlorophenylimino)-4-isobutyl-1,3-thiazolidine 
• 285125-43-1 2-(2,3-dichlorophenylimino)-5,5-dimethyl-1,3-thiazolidine 
• 921222-07-3 2-(2,3-dichloro-phenylamino)-6-fluoro-3H-benzoimidazole-4-carboxylic acid methyl ester 
• 921222-15-3 2-(2,3-dichloro-phenylamino)-5-methylsulfanyl-3H-benzoimidazole-4-carboxylic acid ethyl ester 

Relevant articles and documents

COMPOUNDS WITH COPPER- OR ZINC-ACTIVATED TOXICITY AGAINST MICROBIAL INFECTION

Heterocyclic compounds with a novel pyrazole thioamide-based NNSN structural motif, having highly effective zinc- or copper-activated toxicity against microbial infections at micromolar or nanomolar minimum inhibitory concentrations (MIC), and methods of making and using same.

Facile and versatile synthesis of alkyl and aryl isothiocyanates by using triphosgene and cosolvent

A mild and efficient method for the conversion of alkyl and aryl amines to isothiocyanates via dithiocarbamates has been developed using (CH 3)2CO-CS2 as co-solvent and triphosgene as dehydrosulfurization reagent. High yields, mild reaction conditions and excellent functional group compatibility make it become a versatile synthetic method for the preparation of isothiocyanates compared with reported methods. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]